Aug 23, 2017
But the median CD4 count at treatment start is below 350, which means work is needed to catch up to World Health Organization guidelines.
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But the median CD4 count at treatment start is below 350, which means work is needed to catch up to World Health Organization guidelines.
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Background: Vitamin A deficiency (VAD) is a major public health problem in developing countries and a large number of pregnant women, especially in low-income communities, are more susceptible to VAD. This study aimed to report the baseline levels of Vitamin A in pregnant women with and without HIV-1 infection and to ascertain the association of CD4 + count and viral load with vitamin A deficiency. Methodology: A cross-sectional study was conducted in which HIV-1 infected and uninfected pregnant women were recruited. 24hr Dietary recall data were obtained using Windiest software. CD4 T cell counts in HIV-1+ patients were measured using a Pima Analyzer. Serum Vitamin A levels were performed using Enzyme Linked immune-sorbent Assay (ELISA). Results: The mean age of the participants was 27.05± 5.98. The mean Vitamin A levels were 92.41±57.32, and the mean CD4+ count was 631.78±271.29. In the case and control groups, vitamin A levels showed a statistically significant difference (p =0.003). No significant correlation was observed among the VAD, viral load (P=0.79), and CD4+ count (P=0.84). Conclusion: This study concluded that HIV-1-positive pregnant women often suffer from vitamin A insufficiency, and supplementation with vitamin A and other micronutrients is crucial for improving their health outcomes.
Background: Vitamin A deficiency (VAD) is a major public health problem in developing countries and a large number of pregnant women, especially in low-income communities, are more susceptible to VAD. This study aimed to report the baseline levels of Vitamin A in pregnant women with and without HIV-1 infection and to ascertain the association of CD4 + count and viral load with vitamin A deficiency. Methodology: A cross-sectional study was conducted in which HIV-1 infected and uninfected pregnant women were recruited. 24hr Dietary recall data were obtained using Windiest software. CD4 T cell counts in HIV-1+ patients were measured using a Pima Analyzer. Serum Vitamin A levels were performed using Enzyme Linked immune-sorbent Assay (ELISA). Results: The mean age of the participants was 27.05± 5.98. The mean Vitamin A levels were 92.41±57.32, and the mean CD4+ count was 631.78±271.29. In the case and control groups, vitamin A levels showed a statistically significant difference (p =0.003). No significant correlation was observed among the VAD, viral load (P=0.79), and CD4+ count (P=0.84). Conclusion: This study concluded that HIV-1-positive pregnant women often suffer from vitamin A insufficiency, and supplementation with vitamin A and other micronutrients is crucial for improving their health outcomes.
Background: Vitamin A deficiency (VAD) is a major public health problem in developing countries and a large number of pregnant women, especially in low-income communities, are more susceptible to VAD. This study aimed to report the baseline levels of Vitamin A in pregnant women with and without HIV-1 infection and to ascertain the association of CD4 + count and viral load with vitamin A deficiency. Methodology: A cross-sectional study was conducted in which HIV-1 infected and uninfected pregnant women were recruited. 24hr Dietary recall data were obtained using Windiest software. CD4 T cell counts in HIV-1+ patients were measured using a Pima Analyzer. Serum Vitamin A levels were performed using Enzyme Linked immune-sorbent Assay (ELISA). Results: The mean age of the participants was 27.05± 5.98. The mean Vitamin A levels were 92.41±57.32, and the mean CD4+ count was 631.78±271.29. In the case and control groups, vitamin A levels showed a statistically significant difference (p =0.003). No significant correlation was observed among the VAD, viral load (P=0.79), and CD4+ count (P=0.84). Conclusion: This study concluded that HIV-1-positive pregnant women often suffer from vitamin A insufficiency, and supplementation with vitamin A and other micronutrients is crucial for improving their health outcomes.
Why you should start with ART right away
Why you should start with ART right away
Antiretroviral therapy, or ART, is a safe and proven way to treat HIV. Your doctor will want you to start right away — usually the same day you are diagnosed. This is called quick start ART. Early and effective treatment can help you lead a normal life. It can also reduce the chances of you passing the virus on to someone else. The sooner you start ART, the better. That’s true, even if you feel…
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HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART) REGIMENS PRESCRIBED IN STUDY SUBJECTS ATTENDING GOVERNMENT GENERAL HOSPITAL, VIJAYAWADA, ANDHRA PRADESH, INDIA
The object of the present study was to assess the Highly Active Antiretroviral therapy (HAART) regimens prescribed in study subjects attending Government General Hospital, Vijayawada, A.P, India, during April, 2012 to April, 2015. It was the cross-sectional record-based study. Out of 95 HIV infected children recruited for the study, 24 subjects were in pre-HAART era without taking antiretroviral drugs because they have shown CD4 count more than 350 cells/cmm, 60 subjects were in HAART era taking antiretroviral drugs because they have CD4 counts less than 350 cells/cmm and 11 subjects were mortal cases. Out of 60 subjects in HAART era, 29 (4.75%) subjects were on first-line treatment i.e., Stavudine + Lamivudine + Navirapine (SLN) regimen, 19 (32.0%) subjects were on Stavudine + Lamivudine + Efavirenz (SLE) regimen, 7 (12.0%) subjects were on Zidovudine + Lamivudine + Efavirenz (ZLE) regimen, 4 (6.5%) subjects were on Zidovudine + Lamivudine + Navirapine (ZLN) regimen, and only one subject (2.0%) was on Tenofovir containing regimen i.e., Tenofovir Disoproxil Fumarate + Emitricitabine + Efavirenz (TTE) second-line HAART regimen due to severe drug reaction to Zidovudine, Stavudine and Lamivudine containing regimens. 38.0% of male and 23.0% female subjects on SLE regimen were with mean age of 15.1 years, 9.0% of male and 15.0% of female subjects on ZLE regimen were with mean age of 15.5 years, 44.0% of male and 54.0% of female subjects on SLN regimen were with mean age of 15.2 years, 9.0% of male and 4.0% of female subjects on ZLN regimen with mean age of 17.5 years, and one (4%) female subject on TEE regimen with the age of 20 years. On the whole, the majority of the subjects under HAART shown rise in CD4 counts during the course of treatment indicating that regular therapy to HIV infected subjects prolong their life span.
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The 4 CDC Stages of HIV Disease use both CD4 and % according to what I'm reading. What I don't understand is if a person's CD4 nadir was 350, but had a % <14, does that make him Stage 3?
No, the CDC staging system carries this important footnote: “The stage is based primarily on the CD4+ T-lymphocyte count; the CD4+ T-lymphocyte count takes precedence over the CD4 T-lymphocyte percentage, and the percentage is considered only if the count is missing.”
HIV Infection and its Different Stages
HIV Infection and its Different Stages
HIV infection advances to the f stage if not treated, overwhelming your immune system and getting worse over time. By using HIV medicines (called Antiretroviral Therapy or ART) consistently, you can prevent HIV from progressing to AIDS. ART helps control the virus so that you can live a longer, healthier life and reduce the risk of transmitting HIV to others. Three Stages of HIV Infection The…
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