Mar 28, 2020
Season 8 Case 31
History: altered mental status. Weakness
Answer: Dyke-Davidoff-Masson Syndrome (DDMS)Â
Early infection/infarction/insult to one of the cerebral hemispheres  -> hemi-cerebral atrophy + homolateral hypertrophy of the skull and sinuses (to fill the space)Â
CT shows large area of encephalomalacia of the R MCA distribution + R calvarial thickening and hyperpneumatization of the frontal sinusesÂ
Bony findings are apparent on the X-ray, just a little more difficult to appreciate (in fact originally described on plain films I believe)
Clinically patients are young presenting with hemiparesis (contralateral of course), seizures and intellectual disability
