Have btb or similar treatments lost their efficacy? You could be suffering from Tox Blox which is on the rise and results to the formation of antibodies that counteract the effects of neurotoxins such as Botox, Dysport or Xeomin. These antibodies counteract the remedy and do not affect the creases and muscular spasms. Now, what’s encouraging, is that doesn’t mean that all avenues of hope are out the window. Perhaps replacing Xeomin for the one that does not have neurotoxin-associated proteins that cause antibodies formation will assist. Another kind of treatment is Myobloc, which might also bring comfort to those who fail on other types of treatments.