Autoimmune hypophysitis is a rare cause of pan-hypopituitarism. Hypothalamic involvement in autoimmune hypophysitis is rare and usually mani
“a middle aged man who presented to us with the complaints of documented body temperature fluctuations since two months followed gradually by hoarseness of voice, sexual dysfunction and syncope.”
“alternating periods of excessive heat and cold intolerance and body sweating which was associated with excessive shivering and documented fluctuations in body temperature throughout the day since past two months”
“hormone profile revealed pan-hypopituitarism and elevated titre of anti-TPO antibodies”
“treated with prednisolone along with hormone replacement. Rapid response within 30 days was observed in the form of subsidence of temperature fluctuations, improvement in general well being, sexual function”
“patient was empirically started on hormone therapy in the form of prednisolone (60mg/day), levothyroxine (75 mcg/day) and testosterone. Patient improved symptomatically within 30 d of treatment and his temperature fluctuations subsided and there was an improvement in general well being and sexual function”
