Aug 29, 2024
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Researchers developed a novel method to turn off prion protein production in mice. The technique could lead to treatments for prion diseases
Nessa vida é eita atrás de eita.
Prions are the protein-based infectious agents responsible for prion diseases. Environmental prion contamination has been implicated in dise
me when i research prions and go to sleep perfectly fine (the previous sentence is a work of fiction) (i will continue researching prions despite this)
Eu observo as estrelas,
procurando respostas sobre como deveriamos ser.
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Prion diseases are transmissible neurodegenerative conditions affecting human and a wide range of animal species. The pathogenesis of prion
“EUE is a TSE of exotic zoo ruminants of the family Bovidae. During a period overlapping with BSE epidemic, 6 greater kudu, 6 elands, 2 each of Arabian oryx and ankole cattle, and 1 each of gemsbok, nyala, scimitar-horned oryx and bison were diagnosed with EUE from UK. The affected animals had been fed meat and bone meal (MBM) derived from ruminants.”
from PMC - An Overview of Animal Prion Diseases -> Exotic Ungulate Encephalopathy
From the National Library of Medicine, Kuru prions and sporadic Creutzfeldt-Jakob disease prions have equivalent transmission properties in transgenic and wild-type mice -> Results by Jonathan D. F. Wadsworth, Susan Joiner, Jacqueline M. Linehan, Melanie Desbruslais, Katie Fox, Sharon Cooper, Sabrina Cronier, Emmanuel A. Asante, Simon Mead, Sebastien Brandner, Andrew F. Hill, and John Collinge
Kuru provides our principal experience of an epidemic human prion disease and primarily affected the Fore linguistic group of the Eastern Hi
From the National Library of Medicine, Protein Folding in the Cytoplasm and the Heat Shock Response -> The Cytosolic Chaperone Machinery by R. Martin Vabulas, Swasti Raychaudhuri, Manajit Hayer-Hartl, and F. Ulrich Hartl
Proteins generally must fold into precise three-dimensional conformations to fulfill their biological functions. In the cell, this fundament