#astelin

Brand Name: Astelin, Astepro

Generic Available

Common Dosage Forms:

Nasal Spray (Astelin): 0.1% azelastine. Each spray delivers 137 mcg azelastine HCL.

Nasal Spray (Astepro): 0.15% azelastine. Each spray delivers 205.5 mcg of azelastine HCL.

FDA Indications/Dosages:

For the treatment of the symptoms of nonallergic vasomotor rhinitis and seasonal allergic rhinitis such as rhinorrhea, sneezing, and nasal pruritus in adults and children 12 years and older: The recommended dose is two sprays per nostril twice daily. After assembly prime the pump by spraying 4 times. No additional priming is necessary unless more than 3 days lapse between doses.

Pharmacology/Pharmacokinetics: Azelastine is a histamine H1-receptor antagonist that blocks histamine release in peripheral tissues. Systemic bioavailability after intranasal administration is approximately 40%. Cmax occurs in 2-3 hours. Elimination half-life is 22 hours. Azelastine is metabolized by the cytochrome P450 enzyme system to an active metabolite, desmethylazelastine.

Drug Interactions: Other CNS depressants may increase drowsiness. Cimetidine may increase effects.

Contraindications/Precautions: Contraindicated in patients who are hypersensitive to any of its components. May cause drowsiness, use cautions when performing activities that require alertness. Pregnancy Category C.

Adverse Effects: Bitter taste in mouth (20%), headache (14%), drowsiness (12%), nasal burning (4%), pharyngitis (4%), dry mouth, sneezing, nausea (3%), rhinitis, fatigue, dizziness, nosebleed, and weight increase (2%).

Patient Consultation:

May cause drowsiness. Use care when operating machinery or when mental alertness is required.

Carefully read the enclosed patient information sheet before using.

Store units upright in a cool place away from sunlight and children. Keep the pump unit tightly closed. Unit need to be primed with 4 sprays upon assembly and with 2 sprays if not used for 3 days.

Azelastine is used to relieve nasal symptoms such as runny/itching/stuffy nose, sneezing, and post-nasal drip caused by seasonal allergies and other allergic conditions. This medication is an antihistamine. It works by blocking certain natural substances called histamines that are responsible for allergic symptoms.

Astelin contain Azelastine, an antihistamine, is utilized to relief of hypersensitive rhinitis. This is the point at which within the nose is aggravated and chafed, and it is normally brought on by feed fever and different hypersensitivities. Introduction to aggravations, for example, plant dusts, pet hide or contamination can result in the body to discharge compound called histamine. The arrival of histamine causes the covering of the nose to wind up swollen and irritated which thus causes wheezing, a blocked nose, or a sore and constantly runny nose. By obstructing the activity of histamine, azelastine nasal splash serves to soothe these indications. Step by step instructions to utilize Azelastine nasal spray:

Blow your nose delicately.

Remove the top. The first occasion when you utilize the splash, press down on the neckline of the jug a few times until you see a fine spread. Do this into the air, far from your face.

Hold one nostril shut with a finger, and after that keeping your head upright or tilted somewhat advances, embed the spout of the splash into the other nostril. Press down on the neckline of the container to regulate one shower. Don't tilt your head regressively as you do this.

Repeat the above venture in the other nostril.

Wipe the spout with a clean tissue, and afterward supplant the top.

Important Information:

use one spread in every nostril twice a day, in the morning and night.

If you neglect to utilize the spread, use it when you recollect and afterward proceed as some time recently.

Azelastine nasal spreads ought to just be utilized by one individual. The spread is for you, don't offer it to others regardless of the possibility that their condition shows up the same as yours.

Do not utilize the spread more frequently than your specialist or drug specialist suggests, as this can build the danger of reactions.

if you are utilizing azelastine nasal splash to ease the side effects of roughage fever, your specialist or drug specialist is liable to prescribe that you begin utilizing the spread 2-3 prior weeks the feed fever season begins.

Astelin hold Azelastine is utilized to diminish nasal manifestations, for example, runny/tingling/stuffy nose, wheezing, and post-nasal trickle brought about via occasional anaphylaxes and other unfavorably susceptible conditions. This pharmaceutical is an antihistamine. It works by hindering certain common substances called histamines that are in charge of hypersensitive side effects. Prrcautions:

Before utilizing Azelastine Nasal spray, tell your specialist or drug specialist on the off chance that you are hypersensitive to it; or in the event that you have any viable anaphylaxes. This item may hold inert elements.

This medication may make you lazy. Don't drive, use hardware, or do any action that obliges sharpness until you are certain you can perform such exercises securely. Limit jazzed up drinks.

This prescription ought to be utilized just when obviously required amid pregnancy. Talk about the dangers and profits with your specialist.

It is not known whether this medication passes into breast milk. Counsel your specialist before breast sustaining.

Fexofenadine dosages instruction online     Astelin contains Azelastine hydrochloride  as an active ingredient. Astelin is an antihistamine which is designed for treating allergy symptoms such as sneezing and itchy, runny nose. It is also used to treat symptoms of nasal passage inflammation such as runny nose, stuffy nose, and postnasal drip.  Mechanism of action:      Histamine can produce symptoms of itching, sneezing, watery eyes, and runny nose. Astelin works by blocking the action of histamine, which reduces allergy symptoms. Precautions:

Take exactly as prescribed by your physician. 

Do not take in larger or smaller amounts or for longer than recommended.

Consuming alcohol can increase certain side effects of azelastine.

Do not use this medication if you are allergic to azelastine.

Discus with your physician if you are pregnant or plan to become pregnant while using this medication. It can harm an unborn baby.

Do not take this medication without discussing with your physician if you are breast-feeding a baby.

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Azelastine dosages Side effects: Get emergency medical help if you have any of these symptoms:

rapid heartbeat

hives 

troubled breathing 

tightness in the chest 

swelling of your face, lips, tongue, or throat

Blood in the urine

Common side effects are:

Bitter taste in the mouth

Nosebleeds

drowsiness or sleepiness

headache

dizziness, nausea

weight gain

sore throat

Astelin which contain Azelastineis a potent, second-generation, selective, histamine antagonist (histamine-H1-receptor antagonist). According to the Allergic Rhinitis and its Impact on Asthma (ARIA) treatment guidelines, intranasal anti-histamines are recommended for the first line therapy of mild intermittent, moderate/severe intermittent and mild persistent rhinitis (new classification system for rhinitis). Indications and Usage Treatment of symptoms of seasonal allergic rhinitis, such as rhinorrhea, sneezing, and nasal pruritus (nasal spray); treatment of symptoms of vasomotor rhinitis, such as rhinorrhea, nasal congestion, and postnasal drip ( Astelin only); treatment of symptoms of perennial allergic rhinitis ( Astepro only); treatment of itching of eye associated with allergic conjunctivitis (ophthalmic). Mechanism of action: Azelastine competes with histamine for the H1-receptor sites on effector cells and acts as an antagonist by inhibiting the release of histamine and other mediators involved in the allergic response. Side effects:

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using azelastine and call your doctor at once if you have any of these serious side effects:

bronchospasm (shortness of breath, tightness in chest, wheezing); or

fast or uneven heartbeats.

Less serious side effects may include:

a bitter taste in your mouth;

headache;

drowsiness or dizziness;

dry mouth, sore throat;

burning in your