The Amiot 143M was a late 1930s French medium bomber. The Amiot 143M entered service in July 1935, with deliveries continuing in 1936 and 1937. At the outbreak of the Second World War, Amiot 143s equipped 5 metropolitan groupes together with a single African based groupe.

Following the start of the Battle of France, the Amiot 143M was mainly used in night attacks against German airfields and lines of communications. One notable exception was a daylight raid by 10 Amiots from GBs I/34, II/34 and II/38 led by Commandant de Laubier against German bridgeheads near Sedan on 14 May 1940. Despite fighter escort, two Amiots were shot down while a third force-landed before reaching its base.

Some planes of II/38 served as transports for the French in Syria. This groupe later went over to the Allies after their landings in Africa. The last Amiot 143M was retired from service in February 1944.

A few Amiot 143M were commandeered by the Germans and used as transports.

The Amiot 150 was a reconnaissance, torpedo bomber prototype, designed for use with the Aeronavale. It was an Amiot 143 with 10% larger wing, interchangeable wheel or float landing gear, powered by two 559.3 kW Gnome-Rhône 14Kdrs radial engines. Only one prototype was built.