#aav capsids

Wyss Institute Researchers Demonstrate Machine-Guided Engineering of AAV Capsids for Gene Therapy

High-throughput synthetic biology approach reveals hidden AAV features and could help fast-track future gene therapies

Adeno-associated viruses (AAVs) have become the go-to vehicle for delivering therapeutic gene cargo to target tissues for the wave of gene therapies that are in development in academic and biotechnology laboratories. However, natural AAVs do not specifically target diseased…