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An outline on Generic Viagra

Generic Viagra is the generic equivalent of the brand Viagra, which has same action as that of Viagra. It is available at lower price than the branded version Viagra. It is the cost effective alternative to Viagra. Both the generic and branded version contain Sildenafil citrate as the active component. Sildenafil citrate was the first effective drug approved for the treatment of erectile dysfunction in men by Food and Drug Administration (FDA) in the year 1998. After six months of its approval by FDA, millions of prescriptions were written for Generic Viagra. It is a powerful cGMP-specific phosphodiesterase type 5 (PDE-5) inhibitor. It is a prescription based medicine. You need a doctor’s prescription for purchasing generic Viagra.

What is Erectile Dysfunction?

Erectile dysfunction termed as ED is a type of sexual disorder in men in which a man is not able to get or maintain an erection of penis for long duration of time.

Mechanism of Action of Generic Viagra

Generic Viagra prevents the degradation of cGMP by inhibiting PDE-5 enzyme which increases the concentration of cGMP, causing relaxation of smooth muscles inside penis and dilation of blood vessels responsible for supplying blood to the penis. The dilated blood vessels are wider in size that let more amount of blood to enter the penis which results in a firm and strong penile erection required for successful vaginal penetration. Both partners obtain complete sexual satisfaction and complete sexual pleasure.

Onset of action and Duration of effect

The action of this medicine is observed in 30 minutes to 120 minutes after taking the medicine. The onset of action differs from person to person. The effect of this medicine continues for period of 4 hours.

Dosing Instructions

•  Do not consume excess amount or lesser amount of drug than advised by the physician

•  The most extensively prescribed dose of Generic Viagra is 100mg daily

•  This medicine has to be taken 45 minutes to 60 minutes before having sexual intercourse

•  Swallow the medicine as a whole with a full glass of water

•  Generic Viagra 100mg can be consumed with or without food

•  Do not split, chew or crush the tablet

Precautions and Warnings

Tell your doctor about your complete medical history before starting treatment with this medicine. Do not engage in driving and operating machinery while taking Generic Viagra as it may induce drowsiness.

The usage of Generic Viagra in pregnant women, nursing mothers and men below 18 years of age should strictly prohibited.

Contraindications

The use of Generic Viagra is contraindicated with

•  Alcohol

•  Tobacco

•  Grapefruit or grapefruit juice

•  Nitrate drugs

•  Alpha-blockers

•  Other PDE5 inhibitors

•  Fatty meals

Common Side effects

The following are the common side-effects of Generic Viagra which subside after discontinuing the medicine:

•  Headache

•  Vision Disturbances

•  Back ache and muscle pain

•  Facial Flushing

•  Nasal Congestion

•  Nausea and Vomiting

•  Giddiness

•  Stomach upset

•  Skin inflammation

What is to be done in case of missed dose?

•  Take the missed dose as soon as you remember

•  Skip the dose if it’s already the time to take the next scheduled dose

•  Never take an extra dose to compensate for missed dose

What is to be done in case of an overdose?

Cholesterol, a fatlike matter, travels in the bloodstream in high-density lipoproteins (HDL) called as “good cholesterol” and low-density lipoproteins (LDL) called as “bad cholesterol”. HDL picks up cholesterol and takes it back to the liver for removal. LDL transmits cholesterol to the parts of the body that want it and having excess of it in the bloodstream can cause clogging in blood vessels.

Narrowed or blocked arteries prevent blood from getting through the heart, brain, or other organs. This causes stroke, heart attack, or even heart failure. The liver forms the cholesterol that is needed; however, a huge amount of cholesterol can be obtained from food. In broad-spectrum, high HDL and low LDL aid to decrease the risk of heart disease. Cholesterol is actually needed for the formation or biosynthesis of steroid hormones which are the reproductive or sex hormones present in the body.

The research says

Research has designated that diet and cholesterol show a vital role in heart health and the connection is more complex than it seems.

The link between cholesterol and heart disease

The Dietary Guidelines for Americans explicitly restricted dietary cholesterol to ≤300 milligrams per day and stalwartly endorses eating as little dietary cholesterol as possible. Studies and trials have been mentioned in these guidelines that have produced a firm evidence that healthy eating patterns low in dietary cholesterol can cut the risk of heart disease in adults. In an eight-week study, escalated LDL was a recognized risk factor for heart disease and dietary fatty acids had a significant role in heart disease. It was noted that making minor dietary variations (like replacing a few regularly eaten foods with healthier fat-quality substitutes) abridged cholesterol and could actually reduce future risk of heart disease.

Researchers raise questions

Newer research demands a justification of the role Cholesterol plays in the development of heart disease. In a systematic review, it was revealed that people with high LDL aged over 60 years live as long as or longer than people with low LDL. The investigators recommend reconsidering the guidelines for heart disease deterrence in older adults.

What are the risk factors for heart disease?

•  Having high blood cholesterol •  High blood pressure •  Diabetes and prediabetes •  Family history of heart disease •  Preeclampsia during a pregnancy •  Being overweight or obese •  Physical inactivity •  Unhealthy diet •  Smoking

The risk for heart disease increases with age. For women, the risk rises after menopause.

The chance of developing heart disease rises with each additional risk factor. Some factors, like age and family history, are out of the control. Others, like diet and exercise, are within the control.

What’s the outlook?

Untreated, heart disease can lead to a variety of problems including:

•  Heart damage due to deficiency of oxygen •  Irregular heartbeat (arrhythmia) •  stroke •  Heart attack •  Heart failure

What is an allergy?

Allergy is an abnormal immune response given by the body when it comes in contact with any foreign substance like pollen grains, dust, food, fur etc. This immune response is often harmful to the body. The medical term for an allergy is hypersensitivity. Allergen is the substance which prompts abnormal immune response. Common allergens which produce allergic reaction include pollen grains, dust, animal dander, certain foods, metals insect bites or stings etc.

How is the allergic reaction developed?

The antibodies, which are the part of body’s immune system binds to the allergen and then to mast cells and basophils which are types of white blood cells that help protect the body from any infection or foreign substance. These white blood cells initiate the release of natural chemical substance known as histamine which produce the allergic symptoms.

Dealing with allergies is a complex phenomenon. According to the American College of Allergy, Asthma and Immunology, more than 50 million Americans have some type of allergy.

Most of the time, the body reacts to outdoor and indoor allergens producing mild reactions, such as a runny nose or sneezing. At times, the reaction can be more severe, such as stomach cramps, dizziness or difficulty breathing. Certain people with allergies react in more unusual ways.

What causes an allergic reaction?

Allergies are known to run in families and can be inherited. If you have a close family member who have allergies, you’re at increased risk for developing allergies.

Although the reasons behind developing an allergies are not clearly understood, there are some substances that commonly produce an allergic reaction. People who have allergies are normally allergic to one or more of the following:

•  pet dander

•  bee stings or bites from other insects

•  certain foods, including nuts or shellfish

•  certain medications, such as penicillin or aspirin

•  certain plants

•  pollen or molds

What are the symptoms of an allergic reaction?

The intensity of symptoms of an allergic reaction can vary from mild to severe. If you are exposed to an allergen for the first time, your symptoms may be mild. These symptoms may get worse if you come into contact with the allergen repeatedly.

There are some signs that indicate that you are suffering from an allergy. The most common signs include-

1. Hives- Hives is a common skin rash triggered by several things, including certain foods, medication and stress. Symptoms include itchy, raised, red or skin-colored bumps on the skin's surface.

2. Nasal congestion (known as rhinitis)

3. Runny nose

4. scratchy throat

5. watery or itchy eyes

Treatment of allergies include-

1. Treatment with medicines: Allergic symptoms can be treated with class of drugs known as antihistamines. These medicines work by blocking the action of histamine which is responsible for produces allergic symptoms. The commonly prescribed antihistamines include

•  Fexofenadine (Allegra)

•  Diphenhydramine (Benadryl)

•  Desloratadine (Clarinex)

•  Loratadine (Claritin)

•  Levocetirizine (Xyzal)

•  Cetirizine (Cytec)

Another class of medicine which can help in treatment of allergy includes decongestants .Decongestants help relieve stuffy nose. But decongestants are to be used only for short duration of time. Do not use them for more than three days. The symptoms actually worsen after stopping these medicines. The commonly available decongestants are pseudoephedrine, phenylephrine etc.  Anticholinergic can also be used in treatment of allergy.

You are said to suffer from a migraine if you experience a severe throbbing pain or a pulsing sensation, usually on just one side of the head. This condition often co-exist with nausea, vomiting, and extreme sensitivity to light and sound.

Migraine attacks can cause significant pain that can lasts for hours or days and can be so severe that the pain is disabling.

Warning symptoms like as aura may occur before or with the headache. The warning symptoms also include flashes of light, blind spots, or tingling on one side of the face or in your arm or leg. Medicines can help prevent some migraines and make them less painful. Consult your physician about different treatment options of migraine .The correct medicines, combined with self-help remedies and lifestyle changes, may help treat migraine.

Symptoms

Migraine attacks often begin in childhood, adolescence or early adulthood. Migraines might progress through four stages: prodrome, aura, headache and post-drome, though you may not experience all stages.

Prodrome

One or two days prior to a migraine attack, the person may experience subtle changes that warn of an upcoming migraine, including:

• Constipation • Mood changes, from depression to euphoria • Food cravings • Stiffness in the neck region • Increased thirst and urination • Frequent yawning

Aura

The person may experience Aura may before or during migraines. Most people have migraine attacks without aura. Auras are symptoms of the nervous system. These include visual disturbances, such as flashes of light or wavy, zigzag vision. Sometimes auras can also include touching sensations (sensory), movement (motor) or speech (verbal) disturbances. The muscles may get weak, or you may feel as if someone is touching you. Each of these symptoms usually start gradually, develop over several minutes and lasts for 20 to 60 minutes.

Attack

A migraine typically lasts from four to 72 hours if untreated. The frequency with which the person experience headaches differs from person to person. During a migraine, you may experience:

•  Pain on one side or both sides of your head •  Pain that feels throbbing or pulsing •  Sensitivity to light, sounds, and sometimes smells and touch •  Nausea and vomiting •  Blurred vision •  Light headedness, sometimes followed by fainting

Post-drome

The final stage, known as post-drome, occurs after a migraine attack. Some people may feel exhausted and washed out, while some people feel elated. For a period of 24 hours, you may also experience

•  Confusion •  Moodiness •  Dizziness •  Weakness •  Sensitivity to light and sound

When to see a doctor?

Migraines are often left undiagnosed and untreated. If you frequently experience signs and symptoms of migraine attacks, keep a record of your attacks and how you treated them. Then fix an appointment with your doctor to discuss your headaches.

Visit your doctor immediately or go to the emergency room if you have any of the following signs and symptoms, which may indicate a more serious medical problem:

•  An abrupt, severe headache like a thunderclap •  Headache accompanied with fever, stiffness in neck, mental confusion, seizures, double vision, weakness, numbness or difficulty in speaking •  Headache after a head injury, especially if the headache gets worse •  A chronic headache that gets worse after coughing, exertion, straining or a sudden movement •  New headache pain if you are above 50 years of age.

Causes

Migraine causes are not clearly understood but genetics and environmental factors often  play an important role.

Migraine triggers

Depression is a common but grave problem affecting several people. It produces severe symptoms that affect how you feel, think, and perform daily activities, such as sleeping, eating, or working. A person is said to be suffering from depression if he is showing the symptoms of depression for at least two weeks.

Depression is one of the most common mental disorders in the U.S. Research studies indicate that the depression is caused by a combination of genetic, biological, environmental, and psychological factors.

Depression can occur at any age, but often starts in adulthood. Depression, nowadays also affects children and adolescents. Depression, particularly in midlife or older adults, can occur alongwith other serious medical illnesses, such as diabetes, cancer, heart disease, and Parkinson’s disease. These conditions are often worse when depression is present. Sometimes medications taken to treat all these medical illnesses may cause depression as the side effect. A doctor specialized in treating these complex illnesses can prescribe the best treatment.

The five major symptoms of depression seen in individuals include

•  Depressed mood (feelings of sadness or being blue) •  Lack of interest in activities that they previously used to like or enjoy. •  Feelings of worthlessness •  Poor concentration •  Suicidal thoughts or thoughts about death

There are several forms of depression which are slightly different, or they may develop under unique circumstances, such as:

Persistent depressive disorder (also called dysthymia) is a depressed mood that persists for at least two years. A person suffering from persistent depressive disorder may have episodes of major depression along with periods of less severe symptoms, but symptoms should last for two years to be considered persistent depressive disorder.

Postpartum depression is much graver than the “baby blues” which is a relatively mild depression and anxiety that typically clear within two weeks after delivery.

Psychotic depression occurs when a person experiences severe depression alongwith some form of psychosis, such as having disturbing false fixed beliefs (delusions) or hearing or seeing displeasing things that others cannot hear or see (hallucinations).

Seasonal affective disorder is characterized by the onset of depression during the months of winter, when there is a reduced amount of natural sunlight. This depression generally lifts on arrival of spring and summer. Winter depression shows typical symptoms like social withdrawal, increased sleep, and weight gain.

There are many reasons and excuses for not working out and having fitness fails. Rather the truth is, these unsuccessful attempts and expedient excuses adds up to unavoidable breakdown of the physical and mental wellness and exercise is important for keeping you physical and mental self, healthy and hearty. Here are some tips to stay motivated on getting your fitness goals.

1. Set a precise goal

Just thinking and saying to yourself that I want to become healthy is just not going to work. Set a specific goal like running a 5k or losing 10lbs. Just be sure the goal is real and ascribe a time frame to it.

2. Goal should be realistic

As far as time frames are concerned, goals should be realistic. For example losing 10lbs in a month is highly unlikely whereas same is more realistic to achieve in two to three months. Be honest with yourself about the requirements of goal, resources you put in it, and then calculate the time taken to achieve it. Being impractical with goals can lead you towards failure and will precipitate a viscid cycle of deterrence that is simply needless and unaccommodating.

3. Establish a why

As we all know that there are no gains without pain, everything which is worth needs some work and sacrifice, work which is worth. When it comes to health goals, establishing a ‘why’ makes you achieve it anyhow. Think of the ways your life will improve and remember everything you want for yourself.  There is no reason too deep or superficial as long as it matters to you.

4. Make an inspiration board

Accumulate a horde of inspirational images and messages to reach your weight loss goal like a picture of your favorite bathing suit; favorite motivational quotes; a photo of slimmer you etc.

5. Recruit Support

Public is an enormous help when it comes to stabbing with your healthy routine. Join a running group, yoga class, or a supportive fitness community that helps you stay motivated.

6. Don’t let one slip up derail you

Perfection cannot be achieved every time. Missing a workout occasionally or eat something unhealthy can happen. Just get back on the carriage, get a flat tire, fix it and move on. Continue your workout with determination.

7. Start small