hoes mad your majesty

i'm not super familiar with US law, so i can really only fabulate and i don't think that's very helpful, but sure. there are firstly differences between states that could be important (like if it's a stand your ground state or not), but discounting the general possibility of acquittal for insufficient evidence, i would guess it depends on the nature of the harassment.

to my understanding, assault doesn't require physical contact in every state, so if the harassment crosses that line you could claim self defense and be acquitted if your response seems reasonable and proportional. other than that it'd probably be difficult. most (possibly all?) legal systems very strictly distinguish between words and actions, with the latter treated as much more grave, so a punch in response to verbal provocation would still most likely have you found guilty, although the sentence would probably be lowered.