Another scribbly animation
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Another scribbly animation

Anya is live and ready to show you everything. Watch her strip, dance, and perform exclusive shows just for you. Interact in real-time and make your fantasies come true.
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painter for a season
insta/bluesky/ store/cara
When Drugs Became Available
Have you ever been writing some historical fiction and wondered "hey, I wonder if my characters would have been able to pop an ibuprofen in 1977?" Well, you're in luck, because this post is all about when common medications became available:
Acetaminophen: 1950
Albuterol: 1969 (UK) 1982 (US)
Allopurinol: 1966
Alprazolam: 1981
Amitriptyline: 1961
Amlodipine: 1990
Amoxicilin: 1972
Amphetamine/Dextroamphetamine (together as Adderall): 1996
Apixiban: 2012
Aripiprazole: 2002
Aspirin (first NSAID): 1899
Azidothymidine (first antiviral): 1987
Barbital (first barbiturate): 1903
Bupropion: 1985
Buspirone: 1986
Calcium Carbonate (TUMS): 1930
Captopril (first ACE inhibitor): 1981
Chlordiazepoxide (first benzodiazepine): 1960
Chlorothiazide (first thiazide diuretic): 1957
Chlorpromazine (first antipsychotic): 1952
Cyclobenzeprine: 1977
Diphenhydramine: 1946
Furosemide: 1959
Fluoxetine (first SSRI): 1988
Gabapentin: 1993
Glipizide: 1984
Hydrochlorothiazide: 1959
Ibuprofen: 1969 (UK) 1974 (US)
Insulin: 1923 (though many types of insulins would become available over the next century)
Imipramine (first tricyclic antidepressant): 1959
Iproniazid (first antidepressant (MAOI)): 1952
Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)
Lisinopril: 1987
Lithium: 1949
Losartan (first ARB): 1995
Lovastatin (first statin): 1987
Naproxen: 1976 (Rx) 1990 (OTC)
Nitrogen Mustard (first chemotherapy agent): early 1940's
Methotrexate: 1947
Methylphenidate: 1954
Metformin: 1957 (France) 1995 (US)
Metoprolol: 1978
Montelukast: 1998
Morphine: early 1800's
Omeprazole: 1989
Penicillin: 1945
Phenbezamine (first antihistamine): 1942
Prednisone: 1955
Propranolol (first beta blocker): 1965 (UK) 1967 (US)
Sertraline: 1990
Spironolactone: 1959
Sulfanilamide (first modern antibiotic): 1935
Tolbutamide (first oral anti-diabetic drug): 1956
Tramadol: 1977 (Germany) 1995 (US)
Trazodone: 1981
Valacyclovir: 1995
Verapamil (first calcium channel blocker): 1964
Warfarin: 1954
Zopiclone (first "Z-drug"): 1986
Someone asked for this list in date order, so here it is!
Morphine: early 1800's
Aspirin (first NSAID): 1899
Barbital (first barbiturate): 1903
Insulin: 1923 (though many types of insulins would become available over the next century)
Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)
Calcium Carbonate (TUMS): 1930
Sulfanilamide (first modern antibiotic): 1935
Nitrogen Mustard (first chemotherapy agent): early 1940's
Phenbezamine (first antihistamine): 1942
Penicillin: 1945
Diphenhydramine: 1946
Methotrexate: 1947
Lithium: 1949
Acetaminophen: 1950
Chlorpromazine (first antipsychotic): 1952
Iproniazid (first antidepressant (MAOI)): 1952
Methylphenidate: 1954
Warfarin: 1954
Prednisone: 1955
Tolbutamide (first oral anti-diabetic drug): 1956
Chlorothiazide (first thiazide diuretic): 1957
Metformin: 1957 (France) 1995 (US)
Furosemide: 1959
Hydrochlorothiazide: 1959
Spironolactone: 1959
Imipramine (first tricyclic antidepressant): 1959
Chlordiazepoxide (first benzodiazepine): 1960
Amitriptyline: 1961
Verapamil (first calcium channel blocker): 1964
Propranolol (first beta blocker): 1965 (UK) 1967 (US)
Allopurinol: 1966
Albuterol: 1969 (UK) 1982 (US)
Ibuprofen: 1969 (UK) 1974 (US)
Amoxicilin: 1972
Naproxen: 1976 (Rx) 1990 (OTC)
Cyclobenzeprine: 1977
Tramadol: 1977 (Germany) 1995 (US)
Metoprolol: 1978
Captopril (first ACE inhibitor): 1981
Trazodone: 1981
Alprazolam: 1981
Glipizide: 1984
Bupropion: 1985
Buspirone: 1986
Zopiclone (first "Z-drug"): 1986
Lovastatin (first statin): 1987
Azidothymidine (first antiviral): 1987
Lisinopril: 1987
Fluoxetine (first SSRI): 1988
Omeprazole: 1989
Amlodipine: 1990
Sertraline: 1990
Gabapentin: 1993
Losartan (first ARB): 1995
Valacyclovir: 1995
Amphetamine/Dextroamphetamine (together as Adderall): 1996
Montelukast: 1998
Aripiprazole: 2002
Apixiban: 2012
pretty boy

Anya is live and ready to show you everything. Watch her strip, dance, and perform exclusive shows just for you. Interact in real-time and make your fantasies come true.
Free to watch • No registration required • HD streaming
Navajo sisters. Monument Valley, 1954. The names of the girls on the right are mentioned; Rosie and Ruth. Photo was taken by Ray Manley. Scanned from the magazine Arizona Highways; July 1955
In light of recent events, I have begun submitting bug reports when I see mature content labels applied inappropriately to posts, especially if an appeal has been rejected.
Extremely good idea - how are you doing it? Through the contact us option?
Yeah it’s one of the options on the Contact Support form:
for what it's worth: after a few months of submitting help tickets as 'feedback' when i saw a post inappropriately flagged as mature, i tried following this suggestion instead. today i got my first-ever response from tumblr support on this issue, letting me know that a post i'd submitted a ticket before has had its mature content flag removed.
Hey it worked! Maybe if enough of us make a stink they’ll fix the fucking system.
This is legitimately brilliant. Bug burndown reports (the rate at which your software team can close bugs) is a major metric for most software houses.
It takes an extra step in our part, but this is part of what makes it effective. It's not one click, one reblog activism and it hits them where they care: their damn KPIs.
concurrent events

Anya is live and ready to show you everything. Watch her strip, dance, and perform exclusive shows just for you. Interact in real-time and make your fantasies come true.
Free to watch • No registration required • HD streaming
Me when I remember something I said ages ago that was wrong or my values no longer align with
That’s so amazing!!!
moodboards to visualize some scents i love 🤍
Men who talk shit about gold diggers underestimate the grit it takes to put up with an insufferable man, even when money is involved. We should be thanking them for their service like they are veterans.
Can't leave this in the tags..
Mr. Business and The Heavy have claimed the role of Luigi's giant goth girlfriends.
sorry i had toooooo draw them

Anya is live and ready to show you everything. Watch her strip, dance, and perform exclusive shows just for you. Interact in real-time and make your fantasies come true.
Free to watch • No registration required • HD streaming
Do you see my vision
The Thrilling Sequel