$LAYYYTER
todays bird
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#extradirty
The Stonewall Inn

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cherry valley forever
ojovivo

β£ Chile in a Photography β£
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hello vonnie
d e v o n
PUT YOUR BEARD IN MY MOUTH
Mike Driver
I'd rather be in outer space πΈ

Jimmy Eat World
Cookie Run:Kingdom Official!
KIROKAZE
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@imtheannoyingfriend

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If you are attracted to a girl it's important to show her sinister artifacts and relics
other drivers will see your safe distance from the vehicle in front of you and go "is for me? π₯Ί" and then proceed to not use their turn signal before swerving into your lane

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[Trent reznor voice](close as physically possible to the microphone) ssix little monkeys, jumping on the bed.. one fell down, and he bumped his head
When Drugs Became Available
Have you ever been writing some historical fiction and wondered "hey, I wonder if my characters would have been able to pop an ibuprofen in 1977?" Well, you're in luck, because this post is all about when common medications became available:
Acetaminophen: 1950
Albuterol: 1969 (UK) 1982 (US)
Allopurinol: 1966
Alprazolam: 1981
Amitriptyline: 1961
Amlodipine: 1990
Amoxicilin: 1972
Amphetamine/Dextroamphetamine (together as Adderall): 1996
Apixiban: 2012
Aripiprazole: 2002
Aspirin (first NSAID): 1899
Azidothymidine (first antiviral): 1987
Barbital (first barbiturate): 1903
Bupropion: 1985
Buspirone: 1986
Calcium Carbonate (TUMS): 1930
Captopril (first ACE inhibitor): 1981
Chlordiazepoxide (first benzodiazepine): 1960
Chlorothiazide (first thiazide diuretic): 1957
Chlorpromazine (first antipsychotic): 1952
Cyclobenzeprine: 1977
Diphenhydramine: 1946
Furosemide: 1959
Fluoxetine (first SSRI): 1988
Gabapentin: 1993
Glipizide: 1984
Hydrochlorothiazide: 1959
Ibuprofen: 1969 (UK) 1974 (US)
Insulin: 1923 (though many types of insulins would become available over the next century)
Imipramine (first tricyclic antidepressant): 1959
Iproniazid (first antidepressant (MAOI)): 1952
Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)
Lisinopril: 1987
Lithium: 1949
Losartan (first ARB): 1995
Lovastatin (first statin): 1987
Naproxen: 1976 (Rx) 1990 (OTC)
Nitrogen Mustard (first chemotherapy agent): early 1940's
Methotrexate: 1947
Methylphenidate: 1954
Metformin: 1957 (France) 1995 (US)
Metoprolol: 1978
Montelukast: 1998
Morphine: early 1800's
Omeprazole: 1989
Penicillin: 1945
Phenbezamine (first antihistamine): 1942
Prednisone: 1955
Propranolol (first beta blocker): 1965 (UK) 1967 (US)
Sertraline: 1990
Spironolactone: 1959
Sulfanilamide (first modern antibiotic): 1935
Tolbutamide (first oral anti-diabetic drug): 1956
Tramadol: 1977 (Germany) 1995 (US)
Trazodone: 1981
Valacyclovir: 1995
Verapamil (first calcium channel blocker): 1964
Warfarin: 1954
Zopiclone (first "Z-drug"): 1986
Someone asked for this list in date order, so here it is!
Morphine: early 1800's
Aspirin (first NSAID): 1899
Barbital (first barbiturate): 1903
Insulin: 1923 (though many types of insulins would become available over the next century)
Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)
Calcium Carbonate (TUMS): 1930
Sulfanilamide (first modern antibiotic): 1935
Nitrogen Mustard (first chemotherapy agent): early 1940's
Phenbezamine (first antihistamine): 1942
Penicillin: 1945
Diphenhydramine: 1946
Methotrexate: 1947
Lithium: 1949
Acetaminophen: 1950
Chlorpromazine (first antipsychotic): 1952
Iproniazid (first antidepressant (MAOI)): 1952
Methylphenidate: 1954
Warfarin: 1954
Prednisone: 1955
Tolbutamide (first oral anti-diabetic drug): 1956
Chlorothiazide (first thiazide diuretic): 1957
Metformin: 1957 (France) 1995 (US)
Furosemide: 1959
Hydrochlorothiazide: 1959
Spironolactone: 1959
Imipramine (first tricyclic antidepressant): 1959
Chlordiazepoxide (first benzodiazepine): 1960
Amitriptyline: 1961
Verapamil (first calcium channel blocker): 1964
Propranolol (first beta blocker): 1965 (UK) 1967 (US)
Allopurinol: 1966
Albuterol: 1969 (UK) 1982 (US)
Ibuprofen: 1969 (UK) 1974 (US)
Amoxicilin: 1972
Naproxen: 1976 (Rx) 1990 (OTC)
Cyclobenzeprine: 1977
Tramadol: 1977 (Germany) 1995 (US)
Metoprolol: 1978
Captopril (first ACE inhibitor): 1981
Trazodone: 1981
Alprazolam: 1981
Glipizide: 1984
Bupropion: 1985
Buspirone: 1986
Zopiclone (first "Z-drug"): 1986
Lovastatin (first statin): 1987
Azidothymidine (first antiviral): 1987
Lisinopril: 1987
Fluoxetine (first SSRI): 1988
Omeprazole: 1989
Amlodipine: 1990
Sertraline: 1990
Gabapentin: 1993
Losartan (first ARB): 1995
Valacyclovir: 1995
Amphetamine/Dextroamphetamine (together as Adderall): 1996
Montelukast: 1998
Aripiprazole: 2002
Apixiban: 2012
Donβt worry, there was plenty of amphetamine before that. Methamphetamine and dextramphetamine were very popular and available without a prescription in the 1930s.

Anya is live and ready to show you everything. Watch her strip, dance, and perform exclusive shows just for you. Interact in real-time and make your fantasies come true.
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i don't want to sound like a slut, but i need some human interaction
Trying to sleep during a heatwave is a great reminder that all oil executives need to die painful painful deaths
Actually, no, I don't think that friendships dropping like flies in your late 20s and early 30s because no one has time for that between overwork and family obligations and marriage and kids and partners and the ritual of the time slayer is normal and ok. No I don't think deep conversations and spontaneous adventures being replaced with a tired coffee every six months is a normal part of growing up. I don't think that emotional intimacy and soul bonds disintegrating in the face of practical inconvenience is a fact of life. I think that means something is deeply deeply wrong with our society and I will never forgive it for the friends I've lost

Anya is live and ready to show you everything. Watch her strip, dance, and perform exclusive shows just for you. Interact in real-time and make your fantasies come true.
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