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These days, people are increasingly caring about their general health, and in addition to having a healthy diet, some of them may choose some supplements to help prevent cancer.

It is well accepted that inflammation is closely associated with cancer incidence. People with chronic inflammatory diseases are more likely to get gene mutation that can trigger cancers. Some chronic inflammation can induce many cancers including pancreatic cancer, esophageal cancer, liver cancer and colorectal cancer.

Ginsenosides, active components extracted from ginseng, attracted huge attention for their good anticancer properties in the 1960s. Scientists grew interest in this natural medical herb that can not only exerts much toxicity on cancer cells without harming normal cells but also enhance the sensitivity of various resistant cancer cells to conventional chemotherapy.

Recently, a study published in the journal Nature found that the ginsenoside PPD exerts anti-endometriosis effects by suppressing estrogen receptor-mediated inhibition of endometrial stromal cell autophagy and NK cell cytotoxicity.

Ginsenosides are the pharmacologically active components in ginseng that are found to exhibit brilliant anticancer property. A large number of studies have found that ginsenosides can significantly reduce the nephrotoxicity caused by chemotherapy drugs.

Recently, a study published in the journal Science Translational Medicine found that the inflammation induced during surgical wound healing may trigger a metastatic recurrence.

Researchers in the study illustrated ginsenosides work against tumor growth in four major ways, namely, regulating tumor cell cycle, inducing tumor apoptosis, promoting tumor cell differentiation and targeting tumor stem cells.

Rare ginsenosides are metabolites of prototype ginsenosides, Rg3、Rh2、Rh3 、Rk1 、Rk2、aPPT aPPD included. When digested and degraded by enzymes and gut flora, prototype ginsenosides are converted and metabolized into rare ginsenosides with small molecular weights that greatly facilitate their absorption and utilization.

Ginseng (Panax ginseng) has been long used for a traditional medical remedy in different countries. Ginsenosides are the main bioactive compounds in the ginseng exhibiting anticancer properties. Over the years of dedication to the ginseng research, scientists have found the molecular mechanisms of the cancer chemoprevention and chemotherapy of ginsenosides.

Ginseng is the root of plants in the genus Panax such as Panax ginseng, America ginseng and Panax notoginseng, typically characterized by the presence of ginsenosides and gintonin. It is traditionally used in some parts of the world as a popular remedy for various diseases including cancer.

A significant study conducted by Chinese scientists identified the molecular targets of ginsenosides, suggesting that ginsenosides can be promisingly developed into anticancer drugs.

A significant study conducted by Chinese scientists confirms the anticancer efficacy of ginsenosides, which is a good news for those who are in doubt about the anticancer efficacy of ginsenosides. The research team led by Professor Jin Yinghua of the School of Life Sciences at Jilin University successfully identified the anticancer targets of ginsenosides, which …

In addition, researchers from College of Life Sciences, Kyung Hee University in the Republic of Korea published a study in the Iranian Journal of Biotechnology, finding that ginsenoside Rg5: Rk1 reduced intracellular lipid accumulation and exerted an anti-obesity effect on 3T3-L1 mature adipocytes.

Ginsenosides Rk1 and Rg5 exert inhibitory effects on arachidonic acid (AA)-induced platelet aggregation in a dose-dependent manner, according to a study published in the Journal Pharmazie.