Perhaps an odd question, but what's the strangest combination of game genres that you've experienced in the wild?
I'm not sure it's the weirdest, per se, but one that's always stuck with me is this one educational title I played as a kid that was like a choose-your-own-adventure novel crossbred with a 4X strategy game, at two wildly different scales. You'd follow the narrative of the player character's life, and periodically you'd be asked to make some sort of lifestyle choice; after each choice, the game would "zoom in" to the interior of the player character's body, and you'd play a single round of a turn-based strategy game where you'd deploy various types of immune cells to combat invading armies of pathogens, with the resources available to you influenced by the lifestyle choice you'd just made. I'm not sure what the actual story was, because the turn-based strategy layer was so cryptic and poorly balanced that I never survived more than half a dozen turns before dying of strep throat or genital herpes or something.
(I know somebody in the notes is going to say "that's just Osmosis Jones", but a. the immune cells and diseases were not at all anthropomorphised, and b. this was the mid 1990s, so at least half a decade before Osmosis Jones came out!)
