#woundclosure

The veterinary sutures market is experiencing dynamic growth fueled by continuous innovations and an increasing need for superior wound closure solutions in veterinary surgeries globally. As veterinary care standards advance, there is a growing emphasis on products that enhance healing, minimize infection risks, and improve surgical outcomes.

Technological Innovations Driving Market Growth

Recent advancements in veterinary sutures technology have significantly expanded the product landscape:

Absorbable vs. Non-Absorbable Sutures: Innovations in absorbable sutures made from polyglycolic acid, polylactic acid, and other biocompatible polymers offer effective wound support while eliminating the need for suture removal.

Antimicrobial Sutures: Incorporation of antimicrobial coatings helps reduce infection risk, a crucial factor in both small and large animal surgeries.

Barbed Sutures: Self-anchoring barbed sutures are gaining popularity for their ability to reduce surgery time and evenly distribute tension across wounds.

Biodegradable and Natural Fiber Sutures: Development of eco-friendly suture materials aligns with growing environmental concerns within the veterinary industry.

Rising Demand for Advanced Wound Closure in Veterinary Surgeries

The demand for advanced sutures is driven by several factors:

Increase in Veterinary Procedures: Growing pet ownership and enhanced veterinary healthcare services contribute to higher volumes of surgeries requiring effective wound closure.

Focus on Faster Healing and Reduced Complications: Veterinary surgeons prefer sutures that promote rapid tissue regeneration and minimize the risk of wound dehiscence or infection.

Expansion in Large Animal and Equine Surgeries: The rising number of procedures in livestock and equine care also fuels demand for robust and specialized suture products.

Market Trends and Consumer Preferences

Veterinarians are increasingly prioritizing sutures that combine ease of use with high performance:

Pre-Packaged, Sterile Sutures: Ready-to-use sterile sutures reduce preparation time and infection risk.

Customizable Suture Kits: Tailored kits for specific surgeries are gaining traction to improve procedural efficiency.

Growing Interest in Minimally Invasive Surgery: This trend demands finer, specialized sutures that support small incisions and delicate tissue repair.

Industry Response and Strategic Developments

Leading manufacturers are focusing on:

Research & Development: Ongoing innovation to create sutures with enhanced biocompatibility, tensile strength, and antimicrobial properties.

Collaborations: Partnerships with veterinary hospitals and research institutions to test and promote new products.

Education and Training: Offering training programs to veterinarians on best practices for suture selection and wound management.

Conclusion

Injuries can happen at any time, and when they do, the wound closure zipper strip is a quick and effective solution for stopping the bleeding and promoting faster healing. Whether you're in an outdoor adventure, dealing with sports injuries, or facing an emergency, this tool helps you close wounds securely, reduce the risk of infection, and speed up recovery.

Why You Need a Wound Closure Zipper Strip:

Quick Application: Close wounds fast without unnecessary hassle.

Infection Prevention: Keeps the wound edges together, reducing the risk of contamination.

Promotes Healing: Supports faster healing with minimal scarring.

Tissue glue is used as an alternative method for wound closure that is painless, fast, and does not require a follow-up visit for removal. Tissue glue is made from cyanoacrylate compounds. Tissue glue finds application in superficial lacerations, low wound tension, and after placement of deep sutures to close skin.

Bio-adhesive sealants are developed from proteins, collagen, thrombin, fibrin, gelatin, and polysaccharides such as chitosan are used for acute thoracic aortic dissection repair, controlling intraoperative bleeding in vascular procedures, and for soft tissue sealing.

The global tissue glue and bio-adhesive sealants market is estimated to account for US$ 1,509.6 Mn in terms of value in 2019 is expected to reach US$ 2,876.9 Mn by the end of 2027.

Global Tissue Glue and Bio-adhesive Sealants Market: Drivers

Increasing prevalence of bone-related disorders is expected to propel growth of the global tissue glue and bio-adhesive sealants market over the forecast period. For instance, according to the paper ‘New Osteoporotic/Vertebral Compression Fractures’, published in 2018 by National Center for Biotechnology Information (NCBI), the U.S. records 700,000 cases of vertebral compression fractures, annually.

Increasing number of arthroplasty procedures is also expected to aid in growth of the market. For instance, in 2018, the American Academy of Orthopaedic Surgeons (AAOS) and the American Joint Replacement Registry (AJRR) recorded over 1 million patients and over 1.4 million hip and knee arthroplasty procedures.

North America region held dominant position in the global tissue glue and bio-adhesive sealants market in 2018, accounting for 51.5% share in terms of value, followed by Europe.

Global Tissue Glue and Bio-adhesive Sealants Market: Restraints

There are several complications in cemented arthroplasty such as inflammation of surrounding soft tissue and breakdown of cement, which may prompt the need for second arthroplasty surgery. Such risks decrease the demand for cemented arthroplasty, which in turn restrains growth of the global tissue glue and bio-adhesive sealants market to a certain extent.

Moreover, lack of adoption of tissue glue and bio-adhesive sealants in emerging economies is also expected to hamper growth of the market. This can be attributed to lack of awareness regarding the benefits, clinical efficacy, safety, and cost-effectiveness of tissue glue and bio-adhesive sealants compared to substitute products or procedures and tissue repair therapies.

Global Tissue Glue and Bio-adhesive Sealants Market: Opportunities

Increasing number of surgeries and amputations is expected to offer lucrative growth opportunities for players in the global tissue glue and bio-adhesive sealants market. For instance, according to the study, ‘Estimating the Prevalence of Limb Loss in the United States: 2005 to 2050", published in the Archives of Physical Medicine and Rehabilitation, there will be an estimated 3.6 million people in the U.S. living with limb loss by 2050.

Moreover, increasing R&D in tissue glue and bio-adhesive sealants is also expected to aid in growth of the market. For instance, in December 2018, researchers from Uppsala University and Stockholm University reported development of new class of bioinspired calcium phosphate cements that can glue tissues together and bond tissues to metallic and polymeric biomaterials.

Market Trends/Key Takeaways

The market is witnessing increasing adoption of inorganic activities by market players. For instance, in December 2019, CryoLife, Inc. partnered with Misonix for commercialization of CryoLife's NeoPatch product for the treatment of various indications outside of cardiac and vascular surgery. 

Key players in the market are focused on adopting tissue glue and bio-adhesive sealants in reconstruction of peripheral nerves. For instance, in January 2018, Gecko Biomedical received a funding of US$6 million under the Investments for the Future Program for R&D in reconstruction of peripheral nerves using 3D-printed micro-conducts secured by one of the company’s exclusive adhesives.

Regulations

U.S.

U.S. FDA Regulations for Human Cells, Tissues, and Cellular and Tissue-based Products (HCT/Ps)

·         Human cells, tissues, and cellular and tissue-based products (HCT/P's) are regulated by the Center for Devices and Radiological Health (CDRH) 

·         Products are included under Section 361 of PHS Act

·         Premarket review and approval not required; Product regulated solely under Tissue Regulations to control spread of communicable disease (21 CRF 1271)

·         Establishment registration and product listing required (21 CRF 1271 -Subpart B)

These HCT/P's are regulated solely as "361 products" when they meet all of the criteria in 21 CFR 1271.10(a):

·         Bone (including demineralized bone)

·         Ligaments

·         Tendons

·         Fascia

·         Cartilage

·         Ocular tissues (corneas & sclera)

·         Skin

·         Vascular grafts (veins & arteries), except preserved umbilical cord veins

·         Pericardium

·         Amniotic membrane (when used alone (-without added cells-) for ocular repair)

·         Dura mater

·         Heart valve allografts

·         Hematopoietic stem cells derived from peripheral or umbilical cord blood

·         Semen

·         Oocytes

·         Embryos

Value Chain Analysis

Global Tissue Glue and Bio-adhesive Sealants Market: Competitive Landscape

Major players operating in the global tissue glue and bio-adhesive sealants market include, Cryolife, Baxter International Inc., Luna Innovations Incorporated, B. Braun Melsungen AG, Johnson and Johnson, Dentsply Sirona Inc., Cohera Medical, Inc., Chemence Medical, Inc., Tissuemed Ltd., C.R. Bard Inc., and Integra LifeSciences Corporation.

Global Tissue Glue and Bio-adhesive Sealants Market: Key Developments

Key players in the market are focused on product development and approval to expand their product portfolio. For instance, in January 2020, Polyganics received CE marking for LIQOSEAL, its easy-to-use and innovative dural sealant patch.

Key players in the market are focused on adopting MA&A strategies to expand their product portfolio. For instance, in December 2019, Advanced Medical Solutions Group plc., a provider of tissue adhesives,  acquired Biomatlante SA, a developer and manufacturer of surgical biomaterial technologies.

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Industry Trend Analysis: The Global Wound Closure Market is expected to be around $15 billion by 2025. Some of the key driving factors for the market growth are, effectiveness of advanced wound closure products in enabling faster healing of chronic wounds, rising prevalence of chronic diseases around the world and increasing demand for minimally invasive wound closure procedures.

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Key Driving Factors: According to a 2016 study conducted by the National Center for Biotechnology Information (NCBI), it is projected that 1 to 2% of the population in developed countries will experience a chronic wound in their lifetime. The study further states that around 6.5 million patients in the U.S. are affected with chronic wounds every year. With such high prevalence of chronic wounds, the demand for wound closure products is expected to significantly increase during the forecast period. However, high cost of wound closure products can hinder the market growth during the forecast period.

Market Opportunities: With prevalence of unmet medical needs in emerging countries, the major players in the wound closure market can largely benefit from introducing advanced wound closure products in emerging markets. Increasing prevalence of diabetes and other lifestyle diseases around the world are expected to significantly contribute to the rising demand for innovative wound closure products. With development of such products, market players can secure a larger share of the market and sustain their competitive position.

Table of Contents: 1.Introduction 2.Executive Summary 3.Market Overview 4.Wound Closure market, By Product 4.1.Introduction 4.2.The Wound Closure market Assessment and Forecast, By Product, 2016-2025 4.3.Haemostatic and Sealing Agents 4.3.1. Market Assessment and Forecast, By Type, 2016-2025 ($Million) 4.3.2. Market Assessment and Forecast, By Region, 2016-2025 ($Million) 4.3.3. Fibrin Sealant 4.3.3.1.Market Assessment and Forecast, By Region, 2016-2025 ($Million) 4.3.4. Surgical Sealant 4.3.4.1.Market Assessment and Forecast, By Region, 2016-2025 ($Million) 4.3.5. Gelatin-based Sealant 4.3.5.1.Market Assessment and Forecast, By Region, 2016-2025 ($Million) 4.3.6. Human Fibrinogen and Thrombin Fleece 4.3.6.1.Market Assessment and Forecast, By Region, 2016-2025 ($Million) 4.4.Topical Tissue Adhesive 4.4.1. Market Assessment and Forecast, By Region, 2016-2025 ($Million) 4.5.Wound Closure Devices 4.5.1. Market Assessment and Forecast, By Type, 2016-2025 ($Million) 4.5.2. Market Assessment and Forecast, By Region, 2016-2025 ($Million) 4.5.3. Mechanical Stapling Devices 4.5.3.1.Market Assessment and Forecast, By Region, 2016-2025 ($Million) 4.5.4. Ligating Clips 4.5.4.1.Market Assessment and Forecast, By Region, 2016-2025 ($Million) 4.5.5. Wound Closure Strips 4.5.5.1.Market Assessment and Forecast, By Region, 2016-2025 ($Million) To be Continued...

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Product Outlook and Trend Analysis: Haemostatic and sealing agents are used to prevent excess blood loss during surgical repair procedures. Hemostasis refers to the formation of blood clot at the site of injury. Hemostatic agents prevent excess flow of blood either mechanically or by augmenting the coagulation cascade. Topical tissue adhesives also known as skin adhesives are effective in many skin wounds/cuts. They consist of liquid cyanoacrylate monomers that form long chains after polymerization to seal the wound edges. They are generally used to treat superficial skin wounds.

Application Outlook and Trend Analysis: On the basis of applications, the global wound closure market is broadly segmented into chronic and acute wound care. Increase in the number of traumatic wounds and road accidents will favorably contribute to the growth of acute wound care segment over the forecast period. Rising geriatric population around the world and increasing incidence of lifestyle diseases such as diabetes has been majorly responsible for the increase in number of cases of diabetic foot ulcers and pressure ulcers in recent years.

Regional Outlook and Trend Analysis: In 2016, North America held a major share of the global wound closure market due to increasing prevalence of lifestyle diseases such as diabetes. Moreover, increasing number of surgical procedures performed every year is also expected to contribute the growth of North American Wound closure market during the forecast period. Asia-Pacific wound closure market is expected to exhibit significant growth during the forecast period owing to prevalence of unmet medical needs in emerging economies such as India and China and increasing focus on development of healthcare infrastructure in the region.

Competitive Analysis: The major players operating in the global wound closure market focus on developing advanced wound closure products enabling effective and faster healing of wounds in a minimally invasive manner. For instance, in March 2017, Ethicon and DePuySynthes jointly introduced customized wound closure kits (including STRATAFIX Knotless Tissue Control Devices and DERMABOND PRINEO Skin Closure System) to improve outcomes in orthopedic surgery. Such product developments will enable the companies to strengthen their product portfolio to sustain their position in the market. Some of the key players in the global wound closure market are, Smith & Nephew PLC, B. Braun Melsungen AG, 3M Company, Baxter International Inc., DeRoyal Industries, Inc., Johnson & Johnson Services, Inc., Medtronic plc, CryoLife, Inc., Derma Sciences Inc. (acquired by Integra LifeSciences Holdings Corporation) and BSN medical GmbH (acquired by SVENSKA CELLULOSA AKTIEBOLAGET SCA (publ)).

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