#thcuk

The endocannabinoid system, discovered only 2 decades ago, ⠀ ⠀ It is now known to be a major modulator of synaptic activity throughout the brain. ⠀ ⠀ Fine-tuned regulation of synaptic activity is the primary function of our endocannabinoid system and plays a major role in protecting neurons.⠀ ⠀ Actually, we have been posting about cannabis receptors, ⠀ ⠀ If you want to take a look of a full brain scan of the nerve system ⠀ ⠀ Go check it out on our profile page☝️⠀ ⠀ 仅在20年前才发现的内源性大麻素系统⠀ ⠀ 现在已知它是整个大脑中突触活性的主要调节剂。⠀ ⠀ 精细调节的突触活动是我们内源性大麻素系统的主要功能，在保护神经元中起主要作用。⠀ ⠀ 实际上，我们一直在发布有关大麻素受体的信息，⠀ ⠀ 如果您想看一下神经系统的全脑扫描⠀ ⠀ 去我们的个人资料页面上查看☝️⠀ ⠀ #cbduk #cbd #thc #thcuk #chinesehemp #neuroscience #brain #science #neurology (at London, United Kingdom) https://www.instagram.com/p/CKL1DmnHQ2a/?igshid=linp5go8dhct

The G protein-coupled receptor 55 (GPR55) ⠀ ⠀ It is a novel cannabinoid receptor, whose exact role in anxiety remains unknown 🤔 ⠀ ⠀ GPR55 is activated by the plant cannabinoids Δ9 THC 🤭 ⠀ ⠀ The present study was conducted to explore the possible mechanisms 🔍⠀ ⠀ By which GPR55 regulates anxiety and to evaluate the effectiveness in the treatment of anxiety-like symptoms 😃⠀ ⠀ G蛋白偶联受体 (GPR55 )⠀ ⠀ 它是一种新型的大麻素受体，其在焦虑症中的确切作用尚不清楚⠀ ⠀ GPR55被植物大麻素Δ9THC激活 🤭⠀ ⠀ 进行本研究以探讨可能的机制🔍⠀ ⠀ GPR55通过其调节焦虑并评估治疗焦虑样症状的有效性 😃⠀ ⠀ #cbduk #cbd #thc #thcuk #chinesehemp #neuroscience #brain #science #neurology (at London, United Kingdom) https://www.instagram.com/p/CKD2ie_Hx1u/?igshid=sx9cvlez0p7k

TRPV1 (Transient Receptor Potential Cation Channel Subfamily V Member 1) ⠀ ⠀ ⭐TRPV1 receptors are predominantly found in sensory neurons in the spinal cord.⠀ ⠀ ⭐It is a intracellular receptor that can suppress pain sensitivity 😲⠀ ⠀ ⭐It can become upregulated during nerve injury and diabetic neuropathy 😃⠀ ⠀ ⭐TRPV1 could be found in brain neurons and in non-neural cells 🧠 ⠀ ⠀ ⭐It is also an important receptor responsible for intracellular communication 🗣️ ⠀ ⠀ TRPV1 是指“瞬态感受器电位阳离子通道，子类V，成员1⠀ ⠀ ⭐TRPV1受体主要存在于脊髓的感觉神经元中⠀ ⠀ ⭐它是一种细胞内受体，可以抑制疼痛敏感性 😲⠀ ⠀ ⭐在神经损伤和糖尿病性神经病变中可上调而減低痛楚 😃⠀ ⠀ ⭐在脑神经元和非神经细胞中都可以找到TRPV1🧠⠀ ⠀ ⭐它也是负责细胞内通讯的重要受体 🗣️⠀ ⠀ #cbduk #cbd #thc #thcuk #chinesehemp #neuroscience #brain #science #neurology (at London, United Kingdom) https://www.instagram.com/p/CJ-352sHe_B/?igshid=3q470npp1g03

The body has two main cannabinoid receptors — CB1 and CB2⠀ ⠀ 🔥CB1 is expressed primarily in the brain, central nervous system, lungs, liver, and kidneys, ⠀ ⠀ 🔥CB2 is expressed primarily in your immune system 💪 ⠀ ⠀ 🔥CB1 receptors are largely found in the central nervous system, where they regulate a wide variety of brain functions, and sporadically throughout the body including in the skin⠀ ⠀ 🔥CB2 receptors, on the other hand, are mostly found on immune cells, which circulate throughout the body and brain via the bloodstream. They’re also found in the spleen, as well as in some bone 🦴and liver cells.⠀ ⠀ ✅Fun fact⠀ ⠀ CBD does indeed interact with our cannabinoid receptors While THC is an agonist and CBD is an antagonist. It blocks cannabinoid receptors rather than activating them.⠀ ⠀ Which is why CBD is thought to counteract some of the effects produced by THC❗⠀ ⠀ Like this post 👍 if you have learned something new today⠀ ⠀ 人体有两个主要的大麻素受体-CB1和CB2⠀ ⠀ 🔥CB1主要在大脑，中枢神经系统，肺，肝和肾中表达，⠀ ⠀ 🔥CB2主要在免疫系统中 💪⠀ ⠀ 🔥CB1受体主要存在于中枢神经系统中，它们调节多种脑功能，并偶发地分布在整个身体中，包括皮肤中⠀ ⠀ 🔥CB2受体主要在免疫细胞中发现，免疫细胞通过血流遍及人体和大脑。 它们还存在于脾脏以及一些骨骼🦴和肝细胞中。⠀ ⠀ ✅有意思的真相：⠀ ⠀ CBD确实与我们的大麻素受体相互作用，而THC是激动剂，CBD是拮抗剂。 CBD阻止大麻素受体而不是激活它们，这就是为什么认为CBD可以抵消THC产生的某些作用的原因❗⠀ ⠀ 如果您今天学到了新东西, 給这帖子点个赞吧 👍⠀ ⠀ #cbduk #cbd #thc #thcuk #chinesehemp #neuroscience #brain #science #neurology (at London, United Kingdom) https://www.instagram.com/p/CJ5mwOMHK_R/?igshid=1khvxqrjildh3

More about CB1 😃⠀ ⠀ CB1 has two receptor sites ✌️⠀ ⠀ 1️⃣ The main pocket is called the orthosteric site. ⠀ ⠀ 2️⃣ The secondary site is called allosteric site. ⠀ ⠀ A molecule that binds to the secondary site change the shape of the main receptor 🧐⠀ ⠀ Changing the shape changes the sensitivity of the receptor 😮⠀ ⠀ CBD can modulate the effects at the CB1 receptor by downregulating the sensitivity of CB1 to other cannabinoids through the CB1 receptor secondary site 👌⠀ ⠀ 有关CB1的更多信息 😃⠀ ⠀ CB1有两个受体位点 ✌️⠀ ⠀ 1️⃣ 主要的口袋被称为正骨位点⠀ ⠀ 2️⃣ 次要部位称为变构部位⠀ ⠀ 与次要位点结合的分子会改变主要受体的形状 🧐⠀ ⠀ 改变形状会改变接收器的灵敏度 😮⠀ ⠀ CBD可通过下调CB1受体次级位点对其他大麻素的敏感性来调节CB1受体的作用 👌⠀ ⠀ #cbduk #cbd #thc #thcuk #chinesehemp #neuroscience #brain #science #neurology (at London, United Kingdom) https://www.instagram.com/p/CJx9oFVnBd8/?igshid=5vjhxch0ypqk