#stereoinversion

ACS Meeting News: New reaction flips triply substituted alcohols into isonitriles

It’s turnabout time for triply substituted alcohols in a new reaction, which flips the configuration of the alcohols’ central carbon as the compound is transformed into an isonitrile. The reaction provides a shortcut to compounds with tertiary alkylisonitriles or tertiary alkylamines that could make it easier to synthesize natural products and design new pharmaceuticals and materials...