#serological testing

Overview of Global Serological Testing Market:

The Global Serological Testing Market report is a skilful and deep analysis of the present situation and challenges. This report focuses on the key drivers, restraints, Market opportunities, threats and risks for Market major players. It makes available analysis of Market size, shares, growth, segmentation, revenue projection (USD Mn), and regional study till 2027. Analysis and discussion of important industry trends, Market size, Market share estimates are mentioned in the report. Serological Testing Market research document also conducts study on production capacity, consumption, import and export for all major regions across the globe.

The reliable Serological Testing Market report offers a comprehensive overview of the global Market and contains thoughtful insights, facts, historical information, and statistically supported and industry-verified Market data. It also encompasses forecasts using a suitable set of predictions and distinct research methodologies. This industry report is a professional in-depth study on the current state of the Market. The Market report also contains the drivers and restraints for the Serological Testing Market that are derived from SOWT analysis, and also shows what all the recent developments, product launches, joint ventures, mergers and acquisitions by the several key players and brands that are driving the Market by systemic company profiles.

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The Global Serological Testing Market is expected to grow at a CAGR of 6.20% in the forecast period of 2020 to 2027.

Some of most important key factors driving the growth of the Global Serological Testing Market are high prevalence of hepatitis C infection, high prevalence and increase in the incidence rates of acute as well as infectious diseases such as tuberculosis, hepatitis and HIV/AIDS across the globe. Additionallythe new product development and approvals for serological tests for a variety of bacterial and viral infections will flourish various growth opportunities for the serological testing market in the above mentioned forecast period.

Top Leading Key Manufacturers are: Serological Research Institute (SERI), Chembio Diagnostic Systems, Inc., Cellex Inc., Advanced Diagnostics, Inc., Randox Laboratories Ltd., Eurofins Scientific, Abbott, BD, Ortho Clinical Diagnostics, Quest Diagnostics, F. Hoffmann La-Roche Ltd, ELITechGroup, Immucor Inc., Thermo Fisher Scientific, Inc., Beckman Coulter, Inc., BioMedomics Inc., Creative Diagnostics, Henry Schein Inc., Grifols S.A. and others. New product launches and continuous technological innovations are the key strategies adopted by the major players.

In terms of the geographic analysis, Europe region leads the serological testing market owing to the growing prevalence of infectious diseases, well-established health care infrastructure and increase in number of geriatric population in the region. APAC is expected to grow over the forecast period of 2020 to 2027 because of the rise in awareness, and surge in per capita health care expenditure along with the large population base with infectious diseases in emerging countries such as India and China.

Dried Blood Spot testing uses dry spots of blood on a paper card instead of liquid blood/plasma. It is an easy way of collecting, shipping and storing blood samples.

DBS has several advantages over collection of liquid blood.

CAMAG DBS-MS 500 HCT enables a fully automated system capable of barcode based sample ID, automated spraying of an internal standard to the blood spot, followed by sample extraction. The extract is guided online to an analytical system of choice (i.e. MS/MS- MS/LC-MS/PAL-ELISA), and the system is cleaned after each extraction to ensure zero carryover.

Its applications are enormous, from newborn screening, dope testing of athletes, drug testing, serological surveys, therapeutic drug monitoring etc.

Newborn Screening: The traditional punch-and-elute Newborn Screening testing sample collection method is a very labor-intensive process. Automated DBS-MS systems attached to Mass spectrometry analyzers, is a faster way to collect samples where a circular area of the DBS is directly eluted from the filter paper card without any punching.  The advantage of using this is reduced analysis and labor cost while improving the results.

Fig 1: DBS setup for the analysis of newborn screening

Dope testing of Athletes: DBS-MS can be used for anti-doping purposes. It offers a reliable high-throughput analysis with minimum turnaround time. In addition, with the Hematocrit (HCT) detection module, the results can be targeted to a hematocrit value. In 2019, the World Anti-Doping Agency (WADA) announced the development and implementation of DBS for routine analysis for the 2022 Winter Olympics and Paralympic Games in Beijing. The advantages included increased sampling intervals at the same time reducing storage and shipping costs of the samples.

 Drug Testing: The use of DBS in drug screening offers an innovative way to simplify the blood collection process while reducing costs at the same time. It can combine on-site sampling and highly reliable and efficient drug testing, by sampling four small blood spots of about 10-20 uL from the fingertip of the subject and sending the samples to a centralized laboratory, where testing can be done.

Serological Testing: The formation and reduction of IgG and IgM antibodies against SARS-CoV-2 play an important role in epidemiological studies. Researchers have identified that Dried Blood Spot testing (DBS) can be used for serological testing of SARS-CoV-2 antibodies in a simple and hassle-free manner. The advantage of using the DBS-MS 500 HCT (Hematocrit) method is that the sampling numbers for blood based detection of COVID-19 can be increased with accuracy, as the time of analysis is reduced significantly due to automation. By using the DBS-MS 500 HCT, the costs associated with sample processing, storage and shipment can be reduced significantly.

Fig 2: CoVid antibody analysis using DBS-MS 500 HCT for population screening

DBS-MS as an alternative to conventional blood testing is a game changer with multiple benefits.

 References:

Figure 1; CAMAG     Application Note on New-born Screening using DBS-MS.