#sciatic nerve

You know what she says??? "You're a bit young for a cane! :-) Its not like you're disabled! :-) Just keep stretching! :-) You shouldn't feel like you're 70! You're 17! :-)"

well the pain is disabling to the point i have to drastically slow down to get to my classes.

but my friends actually care. My friend's dad is gonna let me use one of his old canes he doesn't need anymore and if it works, i get to keep it, and if it doesn't, i can give it back.

Axon Rebuilding

Unlike the neurons in the central nervous system (CNS), those outside the brain and spinal cord – the peripheral nervous system (PNS) – can regenerate their ‘electrical cable’-like fibres (axons) after injury. Understanding how this happens could be of huge benefit for treating a range of conditions such as stroke, spinal cord injury and others in both the CNS and PNS. Researchers have now discovered in mice that the levels of a protein called RSK1 are higher after sciatic nerve injury. Forcing neurons to over-produce RSK1, caused an increase in two proteins called BDNF and IGF1 that helped regrow the neuron’s axon. Here we see a ‘normal’ neuron (top left) and longer neurons with increased levels of RSK1 (top middle and right). By inhibiting either BDNF (bottom left), IGF1 (bottom middle) or both (bottom right), the regrowth of the axons was impaired, suggesting RSK1 is essential for regeneration of these signal-transmitting projections.

Written by Sophie Arthur

Image adapted from work by Susu Mao, Yuanyuan Chen and Wei Feng, and colleagues

Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, China

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in PLOS Biology, June 2022

A Deep Dive into Our Body’s Silent CommunicatorsThe human body, a marvel of nature, operates with a complexity that often goes unnoticed. Central to this intricate system is the network of nerves, the silent communicators orchestrating our every move, thought, and sensation. Let’s embark on a journey to understand these fascinating elements of our biology.Firstly, consider the brain and spinal…

RELIEVE SCIATIC NERVE PAIN WITH THIS EXERCISE: #findingnaturalcures Side with sciatic nerve pain. 1. Lay down on your back: Bring the right leg towards you and bring the left ankle on your right knee. Use a chair to rest your foot. 2. Gently pull left knee towards you. Hold for 15 seconds; inhale. 3. Gently push left knee away from you. Hold for 15 seconds; exhale. 4. Gently bend both knees to your right. Hold for 15 seconds and come back. Keep breathing.