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Tazemetostat, Obat Pertama untuk Terapi Sarkoma Langka

farmasetika.com – Untuk pertama kalinya, sebuah obat telah disetujui oleh Badan Pengawas Obat dan Makanan AS (Food and Drug Administration/FDA) untuk pengobatan sarkoma epiteloid, subtipe langka sarkoma jaringan lunak yang terjadi pada dewasa muda.

Obat ini adalah tazemetostat (Tazverik, Epizyme Inc), dan bertindak sebagai inhibitor EZH2 methyltransferase. Ini diindikasikan untuk pengobatan…

Kenali Sarkoma, Jenis Kanker ‘Santai’ yang Intai Banyak Remaja

MALANGTODAY.NET – Buat ZensTODAY yang senantiasa dikaruniai kesehatan, ada baiknya waspada jika terdapat benjolan dalam tubuh. Hal itu karena bisa jadi adalah pertanda kanker yang menyerang jaringan ikat seperti otot, lemak, tulang rawan, dan pembuluh darah bernama sarkoma. Sarkoma patut diwaspadai karena cukup mengerikan mengingat jenis kanker itu sama sekali tidak memiliki gejala berbahaya. ahli bedah ortopedi dari Parkway Hospitals, Dr. Leon Foo menjelaskan benjolan yang muncul karena jenis kanker ini tak menimbulkan rasa sakit sehingga kerap diabaikan oleh penderitanya. Baca Juga: Nikmatnya Kerupuk Ternyata Tak Sepadan dengan Ancaman Kesehatan Anda! “Ukurannya bisa bertambah, disertai perubahan warna pada kulit. Tekstur kulit juga bisa semakin gelap, ujar Foo dilansir dari Tempo.co, Kamis (1/11/2018). Senada dengan Foo, konsultan senior onkologi medis, Richard Quek, menjelaskan bahwa perubahan ukuran yang semakin membesar dan bisa tumbuh di bagian tubuh mana saja. “Benjolan berada di bawah kulit, bisa tumbuh semakin besar di bagian tubuh yang terkena seiring waktu. Benjolan bisa berada di bagian tubuh mana saja, di anggota gerak, otot, dada. Perkembangannya dalam hitungan bulan,” ujar Richard dilansir dari Dream.co.id. Baca Juga: 2040, Angka Harapan Hidup di Indonesia Cuma Ranking 6 di ASEAN

Gejala Selain Benjolan

Tak hanya itu, sarkoma memiliki gejala yang berbeda-beda. Jenis kanker ini saja bisa memiliki 70 sub tipe dan bisa menyerang bebragai kelompok usia. Orang dewasa dan remaja adalah yang paling umum terserang kanker jenis ini. “Kasus sarkoma banyak ditemui pada pasien dewasa muda dan remaja. Kelompok usia yang biasanya tidak kita asosiasikan dengan kanker,” tambahnya. Baca Juga: Jarang Cuci Helm, Awas Penyakit Mengerikan Seboroik Mengintai! Selain benjolan, gejala sarkoma yang umum ditemui adalah nyeri tulang, batuk, sesak napas, kembung, dan mudah merasa kenyang. “Langkah pertama adalah menyadari kondisi tubuh sendiri. Kemudian tanyakan pada dokter umum apakah Anda perlu menemui dokter spesialis atau menjalani tes lebih lanjut, misalnya CT scan, MRI, jika gejala Anda tidak hilang setelah pengobatan rutin,” tandasnya.

Penulis: Raka Iskandar Editor: Raka Iskandar

Yes, I’m goingt for that old “ask yourself some stuff” -stuff. Whatever.

I’m starting this blog to tell somebody what happened to me. Basically that’s it. Maybe someone can identify.

Actually I think I’m just starting to “talk”. To tell somebody about all the stuff I can’t talk to anybody. I feel like i’m not able to articulate my feelings about all the happenings in my life to my friends. Even though they are really great friends and they tried really hard to support me and be there for me. But I’m just not able to open up.

Allright. Before I rush things. Let’s get started.

Exactly two years ago, I was getting ready to tell my father, that he’s going to be a graddad. I was really really nervous since it was not planned. It just happenend.

So this one day he called me. I was really busy at work, getting ready for an important meeting with the owners of the company I worked for. I picked up the phone and told him I was busy. He wanted to meet up.

My Father was always very self centered and did very really accept a change of plans. I told him I was busy. But he insisted fiercefully to meet right at the moment. I had no chance. Like always.

We met at an Italian restaurant right across the street, where I worked at. I could tell something unsettling was going on. I didn’t know what was wrong, but I felt that he was very unstrained.

We proceeded to make our orders. We both got pizza.

He then told me he had to get surgery. It’s probably nothing, but it could be really bad he said. He explained to me, he had troubles breathing, while going hiking or for a run. 

They saw a little shadow on the X-Ray. So basically they were going to cut him open and have a look. Retrospectively I think I knew already what was going to happen. I dont know. Maybe it’s just a feeling. Like a deja-vu. You think it happened already but maybe it’s just your brain misinterpreting signals so you think you knew already, when in reality you just realised.

“Okay” I said. “We’ll see. It’s probably just some little thingy.”

-I had to tell him now. Crazy. He didn’t even know I had a girlfriend. I didn’t know.

When I told him about the lifechanging happening, he shifted is chin down amd looked me dead in the eye. He didn’t need to say anything. His eyes were forcing his thought into my head. “Are you serious?!” - No sign of happiness. Exactly what I expected. It’s not that he didnn’t want to be happy. Our family just has a big history of unexpected pregnancies with life altering consequences. All on top of a big pile of bad decisions. I’m no exception to that scenario.

He thought about it for a minute. Than he smiled, lifted his head up and said: “Congratulations!”

He ordered a bottle of wine. Italian red. I was reliefed.

If only I had known. It was the last bottle of red wine we shared. I wouldn’t have rushed back to a meaningless meeting.

I would have sat there and just looked at you, dad.

I would have asked you about life. And what it’s like to be you.

What it’s like to carry all the weight of the world on your shoulders.

What it’s like to feel alone, even though surrounded by friends.

What it’s like to fight yourself.

What it’s like to love somebody more than anything.

What it’s like to already know that time’s up.

I miss you dad. So so much. I wish we could play some guitar together again. I wish we could drive through the countryside. Arguing about anything.

I wish I could look at all the old pictures with you again.

I would give everything just to hug you one more time and tell you how thankful I am for everything you have done for me. For all the things you missed out on, just to be there for me.