Hmmm... this was rather disappointing to read. I did Provenge back in 2012. But then doing some follow up reading I ran across this:
Insight: New doubts about prostate-cancer vaccine Provenge
http://www.reuters.com/article/2012/03/30/us-provenge-idUSBRE82T07420120330
Somewhat disturbing to say the least. The question is, who/what do you believe?Â
I was considered to be the ideal candidate for Provenge. Young (by mCRPC - metastatic castrate resistant prostate cancer standards), still healthy with a functional immune system. In other words, most likely to get the biggest bang for the buck... Did it help? Well, despite some ups and downs since then, I'm still here. Did it cure me? No. But no one claimed it would. The whole idea was to beef up my immune system to help slow the disease progression and buy more time.Â
There will always be controversy and detractors when a "disruptive" therapy emerges. Provenge was the first of its kind for prostate cancer. The opportunity for fudged results exists in any clinical trial. I have no idea if the claims in the Reuters article are true. You'd think that there would have been some major coverage if was. But who knows?..Â
Would I try another immunotherapy drug? Yes, in a heartbeat. Even if Provenge turns out to have been a dud, I still believe immunotherapy and targeted therapy are the future of cancer treatment. There is another prostate cancer immunotherapy treatment called PROSTVAC in phase III trials right now. I'm keeping an eye on it. I'm also paying close attention to the Cabozantinib (targeted) trial for use in PC.