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PeaLut study without control:
PeaLut study without control:
In this study, Esposito et al investigated the altered signal transduction associated with soluble amyloid beta-protein (Abeta) oligomer-mediated neurotoxicity in the hippocampus after treatment with the association of palmitoylethanolamide (PEA) with luteolin (Lut). There was no control of PEA alone, without the phytocompound luteolin.
In in vitro studies a human neuroblastoma cell line was…
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Not co-ultramicronized composite including palmitoylethanolamide and luteolin reduces cell damage but palmitoylethanolamide alone
In a critical letter to the editor the conclusion of a paper supporting the pharmacology of Pealut (Glialia) was discussed. In the studies of the pharmacologists Irene Paterniti, Daniela Impellizzeri, Rosanna Di Paola, Michele Navarra, Salvatore Cuzzocrea and Emanuela Esposito co-ultramicronized PEA and luteolin were tested in several models. However, the results were falsly interpreted in…
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