Results and discussion: Predictions were close to measured permeability classes for many drugs using all prediction methods using metoprolol coefficients as reference marker and high extraction ratio for high permeability. However, some false negative and false positive predictions were observed. This can lead to wrong permeability classification and hence wrong biopharmaceutics classification (BCS). The best method with least false predictions in the studied compounds was using more than 90% metabolism as indicator of high permeability, Hence it is suggested to be used for better permeability classification prediction.

ABSTRACT Quantitative models of petrologic processes require accurate partition coefficients. Our ability to obtain accurate partition coefficients is constrained by their dependence on pressure temperature and composition, and on the experimental an https://www.environmentguru.com/pages/elements/element.aspx?utm_source=dlvr.it&utm_medium=tumblr&id=5320597

C-DepthMethod to Determine Diffusion Coefficientand Partition Coefficient of PCB in Building Materials http://dlvr.it/CJ9t72

That’s all I needed the internet/textbooks to tell me, which neither of them did. So here’s to hoping this will help a fellow student who hates Chemistry out..