Oct 27, 2022
shoutout to leticia and erden being one of the finest couples in manhwa history
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shoutout to leticia and erden being one of the finest couples in manhwa history
Anya is live and ready to show you everything. Watch her strip, dance, and perform exclusive shows just for you. Interact in real-time and make your fantasies come true.
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Happy happy birthday to my husband! To many more trips around the sun and all the adventures along the way. Thanks for being the adultier adult when I need you to be, making me ugly laugh and loving me the way you do. I love you and excited for all the shenanigans we got planned for your birthday weekend! Last night was fun but we got so much more to do! It’s gonna be a good year 🍾✨ #birthdayboy #mysuperhothusband #mshh #birthday (at Tulsa, Oklahoma) https://www.instagram.com/p/CpDeFsDAyrH/?igshid=NGJjMDIxMWI=
Happy happy birthday to my husband! To many more trips around the sun and all the adventures along the way. Thanks for being the adultier adult when I need you to be, making me ugly laugh and loving me the way you do. I love you and excited for all the shenanigans we got planned for your birthday weekend! Last night was fun but we got so much more to do! It’s gonna be a good year 🍾✨ #birthdayboy #mysuperhothusband #mshh #birthday (at Tulsa, Oklahoma) https://www.instagram.com/p/CpDeFsDAyrH/?igshid=NGJjMDIxMWI=
What is mSHH? A Guide to Biotech Semantics and ProteinS
Here's a uniprot summary for mSHH - (Sonic HedgeHog) - no, not the game!
Function: Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction.
SOURCE: http://www.mybiosource.com/prods/Recombinant-Protein/mSHH/SHH/datasheet.php?products_id=143339
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