#mobic

ravagermobic: a gender related to ravagers from ‘minecraft’

for anon! colors are taken from images of ravagers and arranged to somewhat mimic their shape/look, and the term combines ‘ravager’ with the ‘-mobic’ suffix.

flag id: a flag with 7 stripes. in order, they are dark grey-cyan, cyan-grey, dark green-grey, brown-grey, reddish-orange, dark brown-grey, and near-black. end id.

zompiglingender

a gender that is related to zombie piglins from minecraft

this gender can be related to gold, piglins, the nether, bastions, zombies, transformations, or minecraft in general

can be a kingender or a fictigender, but doesnt have to be

term and flag coined by me;; credit isnt required but its preferred!

Drug Class:

NSAID (partially selective)

Indications:

pain

inflammation

arthritis

juvenile idiopathic arthritis (JIA)

renal colic

Doses:

7.5mg, 15mg tabs

1 tab QD

dose determined by doctor, usually starts at 7.5mg

Side Effects:

Fluid retention (edema)

Acute kidney injury (AKI)

Stevens-Johnson syndrome

Manufacturer:

Boehringer Ingelheim

Drug Store:

Jordan Drugstore

Contraindications:

Asthma

Cardiovascular disorders (hypertension)

Gastric acidity/ulcers

3rd trimester of pregnancy (early closure of ductus arteriosus)

Brand Name: Mobic, Vivlodex, Anjeso

Generic Available

Common Dosage Forms:

Tablets (Mobic): 7.5 mg, 15 mg

Capsules (Vivlodex): 5 mg, 10 mg

Injection (Anjeso): 30 mg/mL

FDA Indications:

For the relief of the signs and symptoms of osteoarthritis and rheumatoid arthritis: The recommended starting dose and maintenance dose is 7.5 mg per day. Some patients may receive additional benefit by increasing the dose to 15 mg once daily. The maximum recommended daily dose is 15 mg.

For the relief of the signs and symptoms of periarticular and polyarticular course Juvenile Rheumatoid Arthritis (JRA) in patients 2 years of age and older: The recommended oral dose is 0.125 mg/kg once daily, up to a maximum of 7.5 mg.

Monitor: LFT, RFT

Pharmacology/Pharmacokinetics: The mechanism of action of meloxicam is probably due to inhibition of cyclooxygenase resulting in a decreased biosynthesis of prostaglandins. Peak plasma levels are reached in 4-5 hours with an elimination half-life of 15-20 hours. Steady state plasma levels are reached in 5 days. Metabolism occurs mainly via cytochrome P-450 2C9 and to lesser degree CYP3A4.

Drug Interactions: May increase the serum levels of lithium. May decrease the effects of ACE inhibitors. Cholestyramine the clearance of meloxicam. Adverse effects may increase with other nonsteroidal anti-inflammatory agents and aspirin. Use with caution in patients taking warfarin.

Contraindications/Precautions: Contraindicated in patients hypersensitive to nonsteroidal anti-inflammatory agents or aspirin. Use with extreme caution in patients with advanced renal disease and in patients with a prior history of ulcer disease or GI bleeding. NSAIDS MAY CAUSE AN INCREASED RISK OF SERIOUS CARDIOVASCULAR THROMBOTIC EVENTS, MYOCARDIAL INFARCTION, AND STROKE. NSAIDS HAVE BEEN INVOLVED IN RARE CASES OF GI BLEEDING INCIDENTS. Use with caution in patients with liver impairment, asthma, hypertension, fluid retention, heart failure, bleeding disorders, and in the elderly. NSAIDs should be used with caution during pregnancy because they may cause premature closure of the ductus arteriosus. Pregnancy Category C.

Adverse Effects: The most frequent adverse effects are gastrointestinal in nature and include abdominal pain, diarrhea, dyspepsia, flatulence, and nausea.

Patient Consultation:

Compliance with therapy is essential, may require up to 2 weeks to see noticeable improvement in arthritic conditions.

May be taken with food or milk if GI upset occurs.

Shake suspension well before using.

Concurrent ingestion of alcohol may increase ulcerogenic effect.

Avoid aspirin or products containing aspirin without first consulting a physician.

Store in a cool, dry place away from sunlight and children.

If a dose is missed, take it as soon as possible. If it is closer to the time of your next dose than the dose you missed, skip the missed dose and return to your dosing schedule.