#microflow

Canadian Space Technology: Microflow

https://dailymotion.com/video/x2z43zv

"We choose to go to the moon…because that challenge is one that we are willing to accept, one we are unwilling to postpone, and one which we intend to win.” ~John F. Kennedy   Countless labs are looking into a variety of diseases and animal models down here on Earth, and flow cytometry is one of the most useful tools at an immunologist’s disposal. But, did you know that there are flow cytometry experiments being performed in outer space? Astronauts spend countless hours preparing their bodies for the rigors of outer space and for good reason. Long-term exposure to micro-gravity and space itself causes:

Immunological and hematological dysregulation

Bone demineralization

Muscle loss

Cardiovascular adaptation (fluids are redistributed in the body as it tends to stay near the top of the body)

Sensory motor alterations (headaches, nausea)

Some of these symptoms go away over time, but some (like bone demineralization) can be permanent. Given all of these physiological and immunological changes, it makes sense that scientists are trying to understand how space affects the body and different health conditions. So, this is an interesting area of research...but there are many complications when it comes to trying to use a flow cytometer in space.   Zoolander®, Paramount Pictures.

First and foremost, most flow cytometers are rather large and heavy. The size of the cytometer has to be reduced for storage and economical reasons.

It also needs to be resistant to the shocks and jolts associated with the rocket’s launch into space. You can’t have bolts and screws coming loose during the launch.

Cytometers typically have a lot of waste from the fluidics and operation of the machine. Any fluids (including biohazardous biological samples) used in this machine must be contained properly. The last thing you need is for the machine’s fluids to short-circuit the other equipment on the station.

Pokémon®, 4Kids Entertainment.

Most cytometers use a lot of electricity. But, in space, the electrical supply for the machine shouldn’t drain the ship.

Apollo 13®, Universal Pictures.

And finally, ease of use. Most astronauts, unfortunately, are not avid flow users and are inexperienced with this technique. The machine needs to be simple enough for astronauts to use and gather data with.

Canadian Space Technology: Microflow