#microdosingcannabis

Low dose cannabis is changing the way people in Missouri approach wellness. Missouri Made Marijuana offers insights into safe microdosing, highlighting how small amounts of THC or CBD can provide calmness, better sleep, and reduced stress. Their locally crafted cannabis products are designed for both beginners and experienced users seeking balance. Explore why choosing trusted dispensaries is key to a safe and beneficial cannabis experience.

Discover gentle relief with low dose cannabis—wellness starts with balance.

Cannabis offers incredible therapeutic and recreational benefits, but over time, regular use can lead to tolerance—where you need higher doses to feel the same effects. Thankfully, there are simple ways to prevent cannabis tolerance and continue enjoying all its benefits without overloading your system.

Check out the full article on preventing cannabis tolerance here.

What Causes Cannabis Tolerance?

Cannabis tolerance occurs when your body becomes less responsive to THC, the psychoactive compound in cannabis. This happens because the brain reduces the availability or sensitivity of CB1 receptors that THC binds to. Unlike THC, CBD interacts with your system differently and is less likely to contribute to tolerance.

Top Strategies to Prevent Cannabis Tolerance

1. Alternate Between THC and CBD Strains

Switching to CBD-dominant strains periodically can help your CB1 receptors recover while still providing therapeutic benefits.

Use a high-THC strain during the day.

Switch to a CBD-rich strain like Harlequin in the evening.

2. Rotate Cannabis Strains

Each strain offers a unique mix of cannabinoids and terpenes, which can prevent your body from adapting too quickly.

Start with an energizing strain like Jack Herer.

Rotate to a relaxing strain like Granddaddy Purple after a few weeks.

3. Practice Microdosing

Using small amounts of cannabis can prevent overstimulation of your CB1 receptors while still providing mild effects.

Opt for a low-dose edible (2.5–5mg THC).

Take a single puff instead of multiple from a vape pen.

4. Space Out Your Sessions

Limit your cannabis use to once daily or every other day to give your CB1 receptors time to reset.

5. Adjust Cannabinoid Ratios

Switch to strains with balanced or high CBD-to-THC ratios, like Cannatonic (1:1) or ACDC (20:1).

Signs You May Need to Switch It Up

You need more cannabis to feel the same effects.

The effects don’t last as long.

Cannabis is less effective at managing symptoms like pain or anxiety.

If these happen, try rotating strains, microdosing, or alternating THC and CBD products to reset your system.

Why Personalization Matters

Everyone’s body reacts differently to cannabis. Factors like metabolism, genetics, and consumption habits all influence how quickly tolerance builds.

Experiment with different approaches, such as alternating strains, spacing out use, or combining strategies, to find what works best for your unique needs.