#membranefilter

How Modern Purification Systems Stop Contamination in Pharma Manufacturing

Regulatory authorities require complete compliance with good manufacturing practices (GMP). Explore how advanced ultrafiltration membrane filters keep your operations aligned with strict industry standards and protect against severe batch failures.

PVDF Filter is widely used in protein sequence analysis. These filters are ideal for HPLC sample filtration and general biological sample filtration. Simsii has 13 mm, 25 mm, 30 mm Syringe Filters.  If you are looking for PVDF Syringe Filter, please feel free to call us today at 949-336-8212.

PES Filter is certified for ion chromatography; tissue culture filtration; filtration of proteins and nucleic acids. It is hydrophilic and constructed from the Polyethersulfone polymer membrane.

Simsii's Membrane Filters are versatile and available in varied pore sizes with or without a gridded surface.

How to choose the right Syringe Filter is an essential step for filtration. Various types of membrane materials used for manufacturing syringe filters. In this blog, we will discuss the selection of the right syringe filters.

The Process for selecting a filter

1. Determine the particle size to be retained or filtered.  The Membranes will keep every particle as similar and more significant as compared to their defined pore size.

2. Assess the chemical compatibility of the Membrane Filter with the liquid or gas to be filtered. Consider the chemical resistance properties of all the parts that will contact the filtrate.

3. Depending on the procedure performed, the membrane color or surface pattern may be significant.

4. It includes hydrophilic or hydrophobic membranes with flow rate, temperature, throughput, and sterilization requirements.

Types of Membrane Filter material

1. Cellulose Nitrate (CN): Cellulose Nitrate membrane is a popular membrane that can be used in an analytical filtration and laboratory filtration. CN membrane shows good wetting properties and gives the fast rates of flow with aqueous solutions.

2. Mixed Cellulose Ester membrane: Mixed Cellulose Ester membrane provides a uniform and smoother surface compared to a pure nitrocellulose membrane. This type of layer is helpful to count or analyze particles contained in liquids or captured from aerosols.

3. Cellulose Acetate membrane: Cellulose Acetate membrane is a combination of cellulose triacetate and diacetate that creates a stable layer in both lateral and longitudinal directions. Besides, the membrane has a low static charge, a very low aqueous extractability, and excellent solvent resistance to minor weight molecular alcohols.

4. Polyethersulfone (PES): It is a membrane of hydrophilic having low protein binding. There is no need for external wetting agents are required, resulting in low extractable. PES membrane generally offers a fast flow rate and better chemical resistance than cellulose acetate membranes.

5. Nylon Membrane: Nylon Membrane Filter is durable, hydrophilic and highly adjustable with a high range of the aqueous solutions like alcohols and solvents used in HPLC work.

6. Glass Microfibre: Glass Microfiber filters can be used as a pre-filter for samples with high particulate content. GMF membranes come with a higher pore size than other layers and are tolerant to most solvents.