#kgadependent

Inhibiting KGA-dependent glutaminolysis in mice found to eliminate senescent cells

Credit: University of Tokyo A team of researchers affiliated with a host of institutions across Japan has found that inhibiting kidney-type glutaminase-dependent glutaminolysis in mice can lead to elimination of senescent cells. In their paper published in the journal Science, the group describes using RNA interference to look for enzymes that are required for senescent cell survival and…