Incyte: Driving Jakafi, Bracing For Generic Headwinds
Incyte: Driving Jakafi, Bracing For Generic Headwinds

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Incyte: Driving Jakafi, Bracing For Generic Headwinds
Incyte: Driving Jakafi, Bracing For Generic Headwinds

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FDA Approves Jakafi (ruxolitinib) for the Treatment of Patients with Uncontrolled Polycythemia Vera
The first and only FDA-approved treatment for patients with polycythemia vera (PV) who have had an inadequate response to or are intolerant of hydroxyurea PV is a rare blood cancer associated with overproduction of blood cells that can cause serious cardiovascular complications, such as stroke and heart attack1 Jakafi is the only treatment for patients with PV shown to provide consistent hematocrit control, spleen volume reduction and complete hematological remission by targeting the overactive JAK pathway, a critical component of this disease
The approval of Jakafi represents an important advance for patients with uncontrolled PV. For the first time we are able to provide these patients a treatment that has been shown to provide effective and consistent control of their blood counts and reduce spleen volume,” said Srdan Verstovsek, M.D., Ph.D., Professor, Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center.
How should I take Jakafi?
Take Jakafi exactly as your healthcare provider tells you. Do not change your dose or stop taking Jakafi without first talking to your healthcare provider. You can take Jakafi with or without food. Jakafi may also be given through certain nasogastric tubes. o Tell your healthcare provider if you cannot take Jakafi by mouth. Your healthcare provider will decide if you can take Jakafi through a nasogastric tube. o Ask your healthcare provider to give you specific instruction on how to properly take Jakafi through a nasogastric tube.
Do not drink grapefruit juice while taking Jakafi. Grapefruit juice can affect the amount of Jakafi in your blood. If you take too much Jakafi call your healthcare provider or go to the nearest hospital emergency room right away. Take the bottle of Jakafi with you. If you miss a dose of Jakafi, take your next dose at your regular time. Do not take 2 doses at the same time. You will have regular blood tests during your treatment with Jakafi. Your healthcare provider may change your dose of Jakafi or stop your treatment based on the results of your blood tests.
THE CANCER MEDS ARE HERE. It took nearly two weeks to get them but we did and Miryam just took her first dose. GO GO GADGET SHRINKING SPLEEN. DO THE THING.
(one of the symptoms of myelofibrosis is an enlarged spleen. normally it's the size of a fist. Miryam's is currently larger than most babies and growing. the Jakafi will start shrinking it and treating her symptoms. PRAISE)