Low CSF glucose (hypoglycorrhachia) often triggers immediate concern for meningitis—especially in infants. And in emergencies, starting empiric antibiotics can be the safest first step. But what if the labs evolve in the opposite direction: CRP falls, CSF cell counts normalize, cultures and mNGS are negative—yet CSF glucose stays low?
This video explains when that pattern should raise suspicion for GLUT1 Deficiency Syndrome (GLUT1DS), how CSF-to-blood glucose ratio fits into interpretation, and why symptoms can look like seizures, movement disorders, developmental delay, or even autism-like features.
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