Not meant to be a thirst trap, oops

Building off of a post by @nezuiscool regarding animal behavior; I also believe that Nezu would fight (if necessary) more like an animal on four legs. I’m going to also assume Nezu’s reflexes and general agility surpass standard humans and would use this to his advantage to dodge hits and jump substantial distances to confuse opponents. His small size is also something most people have never fought against — thus giving him the advantage.

I headcanon Nezu using his sharp claws to hit pressure points not requiring as much strength as his main offensive attack. And (if acting as a good hero) having to resist the natural instinct to go for the back of the neck with sharp teeth to sever the spinal cord for a killing blow.