#factor ix

Factor IX-Padua: gene therapy and hemophilia

Hemophilia is a Mendelian disease (which is inherited by the mutation of a single gene) on the X chromosome, the disease is transmitted as a sex-linked character, occurs mainly in males. It is a recessive genetic disease that prevents the proper coagulation of blood. As a result, the wounds of those affected bleed for a longer period of time, leading to hemorrhages both externally and internally.

The First Oral Capsule To Treat Hemophilia

Researchers are working on a pill to treat hemophilia, which would let patients with type B hemophilia have oral formulations of clotting factor IX instead of many weekly injections to keep bleeding under control. The study was funded by National Institute of Biomedical Imaging and Bioengineering. A team of researchers are working under the leadership of Professor Nicholas Peppas at the…

CSL Behring Launches New Drug against Hemophilia B - http://www.healthaim.com/csl-behring-launches-new-drug-hemophilia-b/47724

– The VKA act through competitive inhibition of hepatic synthesis of certain clotting factors vitamin K-dependent: prothrombin (II); proconvertin (VII); factor IX; Factor X (X).

– Protein C and Protein S (coagulation inhibitors) are also vitaminic-K-dependent.

– Two families derivatives indandione (fluindione or Previscan) and coumarin (acenocoumarol or Sintrom®; warfarin or Coumadin®).

– Fixing…