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Scientists studying ancient evolutionary changes recently trained a group of fish to walk on land. Over the course of 8 months, the shape of their bodies changed as they adjusted to the terrestrial lifestyle. (source)
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It has been argued that potentially adaptive changes to protein-coding sequences may often be prevented by natural selection because, even if they are beneficial in one cell type or tissue, they may be detrimental elsewhere in the organism. By contrast, because gene-regulatory sequences are frequently associated with temporally and spatially specific gene-expression patterns, changes in these regions may modify the function of only certain cell types at specific times, making it more likely that they will confer an evolutionary advantage
