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Chondrosarcoma of the finger as a result of Ollier’s disease. Ollier disease is a rare condition that results in benign intraosseous cartilaginous tumours (called enchondroma) forming near growth plate cartilage. In this particular case the chondrosarcoma (a form of bone cancer) may have resulted from an untreated enchondroma, and ultimately the second finger required amputation.
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Researchers identify point of epigenetic methylation which drives cartilage tumour formation.
Researchers identify point of epigenetic methylation which drives cartilage tumour formation. Thoughts health innovators?
Duke researchers have identified that mutations in the isocitrate dehydrogenase (IDH) gene contribute to the formation of benign tumours in cartilage that can be a precursor to malignancies. These benign tumours, known as enchondromas, are associated with severe pain, fractures, and skeletal deformities. They also have the potential to evolve into a cancerous form known as chondrosarcomas. Over…
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My knee has been bothering me for the last four days. It hurts when I bend and straighten it and when any pressure is on it. On the inside part. I don't think I've tripped or anything like that and torn anything but I'm so uncoordinated that it could have happened and I don't remember. It's the same knee with the tumor they didn't want to remove so if it grew and gave me like, a hairline fracture or something, I will be livid. The holidays are going to be ridiculous at work and I need my body to keep up. I'm going to try to get to the doctor asap and in the mean time, buy a knee brace 😖ðŸ˜
Multiple Enchondroma
Enchondroma is one type of benign (noncancerous) cartilage tumor that appears on the inside of the…
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Enchondroma
Benign
Cartilaginous growth in medullary cavity of bone (usually metaphysis)
Hands and feet. Think Regina Phalange.
Usually solitary and no symptoms
Enchondromatosis if multiple enchondromas, 2 types
Ollier Disease =>Â non-hereditary, pain & fracture, may become malignant (chondrosarcoma), last pic.
Maffucci Sd => multiple enchondromas + hemangiomas (note the 4°&5° pics, and how sof tissue in X-ray has signs of inflammation, whereas the last one, doesn´t). Increased risk of becoming malignant, ovarian ca and brain gliomas. =(
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Ollier's Disease
Also known as 'enchondromatosis'
A rare bony condition affecting 1 in 100,000 people
Multiple enchondromas form, usually on short tubular bones e.g. hands, feet
An enchondroma is a benign cartilage cyst
Carries a high risk of skeletal malignancy, incidence of secondary chondrosarcoma may be as high as 25%
