#embolotherapy

Blocking blood vessels by creating embolisms is, under most circumstances, very bad. But researchers are exploring ways to fight cancer by intentionally and strategically creating these blockages. In gas embolotherapy, researchers inject fluid droplets, which can carry chemotherapy drugs, into the bloodstream. Once they circulate into a cancerous tumor, they use ultrasound to vaporize the droplet and create a gas bubble. Those bubbles lodge inside the capillaries of the tumor, starving it of fresh blood and trapping the chemotherapy drugs inside. It’s a one-two punch to the cancer. Without blood flow, the cancer cells die, and, since the cancer-killing drugs get mostly trapped inside the tumor, patients may require lower dosages and endure fewer side effects. The technique is currently in animal testing, but hopefully it will be a valuable therapy for human patients in the future. (Image credit: Chemical & Engineering News; research credit: Y. Feng et al.; via AIP)

[230 Pages Report] The global embolotherapy market is valued at USD 3.4 billion in 2021 and is expected to reach USD 5.0 billion by 2026, at a CAGR of 8.0% during the forecast period. Increasing incidences of peripheral vascular diseases, liver cancer, strokes, and uterine fibroids coupled with rising preference for minimally invasive procedures; increasing investments, funds, and grants by public-private organizations for research; and technological advancements in the market will fuel the market growth over the forecast period.

The major players in the market include Boston Medical Corporation (US), Terumo Medical Systems (Japan), Medtronic (US), Johnson & Johnson (US), and Stryker Corporation (US). Other key players in the embolization therapy market include Sirtex Medical Limited (US), Abbott Laboratories (US), Acandis GmbH (Germany), Balt (France), Cook Medical (US), Kaneka Corporation (Japan), Penumbra, Inc. (US), Merit Medical Systems (US).

The embolotherapy devices market has experienced steady growth over the last decade, owing to the growing target patient population base, which has increased the number of target surgeries performed. CVD is a key target disease; its importance and high prevalence have made it a focus for research on successful and effective therapies. As of 2017, more than 200 million people are suffering from peripheral vascular diseases globally (Source: Elsevier, 2018).

Healthcare markets are witnessing a dearth of well-trained surgeons (including neurosurgeons and radiologists). The Association of American Medical Colleges (US) has estimated a deficit of 41,000 general surgeons in the US by 2025 (Source: Association of American Medical Colleges US, 2017). A shortage of more than 2,300 medical oncologists is expected in the US by 2025 (Source: Journal of Global Oncology).

The availability of effective conventional first-level therapies for the treatment of liver cancer, uterine fibroids, hemorrhagic stroke, and other hemorrhagic conditions is a key restraint to market growth. For instance, therapies such as surgery, chemotherapy, and radiation therapy are preferred options in cancer treatment due to the high awareness among individuals about traditional cancer treatments, low adoption of advanced treatment options (especially in developing countries), and the reluctance among oncologists to shift from conventional treatment options.

The embolotherapy market is witnessing a loss of business, and the trend is expected to continue till December 2020. Unfavorable changes in regulations and guidelines are hampering the growth of this industry. Major regulatory authorities across the globe (such as CDC, WHO, MHRA, TGA, and EMA) have identified that cancer patients are at greater risk of COVID-19 infection than healthy adults. Thus, screening, diagnostic exams, and surgical procedures are being severely restricted or postponed at hospitals and cancer care centers. This is expected to cause disruption in the embolotherapy market.

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