The idea of a Dead Space/Doom crossover is so funny to me because both protagonists would be looking at each other's enemies like "eww what the fuck is that???"
The Slayer, staring at a zombie/possessed with knife hands and no jaw: what the fuck happened here
Isaac, staring at the corpse of a mancubus that exploded when he split it open in a panic: ew ew ew ew ew ew ew ew ew ew

















