Case You may notice the following in the Citrix ADC System Log, either inside the ADC GUI dashboard or via the newnslog log: "Failure- TCP connection successful, but application timed out". This corresponds to Citrix ADC monitors which fluctuate between the DOWN and UP states. For example, the down state lasts for about 4 seconds and then the monitor shows again an UP state. Solution To resolve this issue increase the time-out value, if your network has high latency. In order to change the properties of the Citrix ADC monitor, run the following command in Citrix ADC shell. You need to edit the Response timeout value to a reasonable setting, depending on your network conditions. The response timeout value may not be editable via the GUI, so you will need to use CLI instead. set mon -resptimeout 8 seconds save ns conf Sources https://support.citrix.com/article/CTX215481 https://support.citrix.com/article/CTX207195 https://docs.citrix.com/en-us/citrix-adc/13/load-balancing/load-balancing-configure-monitors/modify-monitor.html Read the full article