#benzamides

Molecular Tinkering Doubles Cancer Drug’s Efficacy

Researchers have packaged a widely used cancer drug into nanoparticles, more than doubling its effectiveness at destroying tumors.

The drug paclitaxel has been used for decades to fight breast, ovarian, lung and other cancers. But its effectiveness has been limited by its small molecular size and insolubility in water—properties that allow the body to clear the drug too quickly, reducing its…

Packaging Cancer Drug into Nanoparticles Double’s Tumor Destroying Efficacy

This is an image of the newly repackaged pharmaceutical under a transmission electron microscope. The dark spots are the water-insoluble cores of the nanoparticles, while the peptide chains are barely visible due to their low electron density and high degree of hydration. Credit: Ashutosh Chilkoti, Duke University

The drug paclitaxel has been used for decades to fight breast, ovarian, lung…