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Aromasin Brings Hormonal Equilibrium by Controlling EstrogensÂ
Aromasin, developed by Dragon Pharma, is a potent aromatase inhibitor that offers recovery optimization after cycles and is used in Post Cycle Therapy (PCT) to combat estrogenic side effects. It is a non-steroidal item that helps stabilize hormonal balance by binding to the Aromatase enzyme, which converts androgens into estrogens. This reduction in estrogen production is crucial for bodybuilders and athletes coming off anabolic steroid cycles. Aromasin is effective in estrogen control, promoting natural testosterone production and minimizing negative feedback.
EXEMESTANE (107868-30-4)
EXEMESTANE (107868-30-4)
Exemestane,brand name Aromasin. It is an Aromatase Inhibitor. The mechanism of action of exemestane is as an Aromatase Inhibitor.It is a steroidal inhibitor of aromatase which effectively blocks estrogen synthesis in postmenopausal women and is used as therapy of estrogen receptor positive breast cancer, usually after resection and after failure of tamoxifen.
Status: In Mass Production
Unit: 25kg/Drum
Capacity: 1390kg/month
Exemestane (107868-30-4) video
Exemestane (107868-30-4) Description
Exemestane,brand name Aromasin. It is an Aromatase Inhibitor. The mechanism of action of exemestane is as an Aromatase Inhibitor.It is a steroidal inhibitor of aromatase which effectively blocks estrogen synthesis in postmenopausal women and is used as therapy of estrogen receptor positive breast cancer, usually after resection and after failure of tamoxifen. Exemestane has been associated with a low rate of serum enzyme elevations during therapy and rare instances of clinically apparent liver injury.
Breast cancer cell growth may be estrogen-dependent. Aromatase (exemestane) is the principal enzyme that converts androgens to estrogens both in pre- and postmenopausal women. While the main source of estrogen (primarily estradiol) is the ovary in premenopausal women, the principal source of circulating estrogens in postmenopausal women is from conversion of adrenal and ovarian androgens (androstenedione and testosterone) to estrogens (estrone and estradiol) by the aromatase enzyme in peripheral tissues. Estrogen deprivation through aromatase inhibition is an effective and selective treatment for some postmenopausal patients with hormone-dependent breast cancer. Exemestane is an irreversible, steroidal aromatase inactivator, structurally related to the natural substrate androstenedione. It acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation, an effect also known as “suicide inhibition”. Exemestane significantly lowers circulating estrogen concentrations in postmenopausal women, but has no detectable effect on the adrenal biosynthesis of corticosteroids or aldosterone. This reduction in serum and tumor concentrations of estrogen delays tumor growth and disease progression. Exemestane has no effect on other enzymes involved in the steroidogenic pathway up to a concentration at least 600 times higher than that inhibiting the aromatase enzyme.
Exemestane (107868-30-4) Specifications
Product Name:Â Exemestane
Chemical Name:Â 6-Methyleneandrosta-1,4-diene-3,17-dione, Aromasin, Exemestano, Exemestanum
Brand Name: Aromasin
Drug Class:Â aromatase inhibitor
CAS Number:Â 107868-30-4
InChIKey:Â BFYIZQONLCFLEV-DAELLWKTSA-N
Molecular Formula: C20H24O2
Molecular Weight: 296.41 g/mol
Monoisotopic Mass:Â 296.178 g/mol
Melting Point: 155.13 °C
Freezing Point: No data available
Biological Half-Life:Â 24 hours
Color:Â White powder
Solubility:Â water solubility Non-soluble
Storage Temperature: -20°C
Application: used to treat breast cancer in post-menopausal women (women who have gone through the menopause
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Gandhi Medicos We are Aromasin 25mg Tablets price Buy Online from India Exporters & Bulk Suppliers from India, If you become pregnant while taking AROMASIN, talk to your doctor immediately to learn about the potential risks to the baby. Taking AROMASIN during pregnancy or within 1 month of becoming pregnant can harm your unborn baby. Use effective birth control (contraceptive) during treatment with AROMASIN and for 1 month after your last dose of AROMASIN.
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