#alphoscerate

"Attempts have been made to treat dementia and cognitive impairment with choline supplements such as lecithin (dietary PC, typically derived from eggs or soy), but a review of all unconfounded, randomized trials comparing lecithin with placebo revealed no particular benefit. Alternatives to choline or lecithin proposed to reverse age-related cognitive decline, were cytidine-diphosphocholine (CDP-choline) and choline alphoscerate (L-alpha-glyceryl-phosphorylcholine). Both are natural, water-soluble compounds providing comparable effects in different conditions. After oral administration, both CDP-choline and choline alphoscerate have been shown to cross the blood–brain barrier and reach the central nervous system ..."

"CDP-choline supplementation activates the synthesis of structural phospholipids in neuronal membranes, increases cerebral metabolism and to enhances various neurotransmitter systems. Clinical studies have documented its effectiveness in mild cognitive impairment, and in the management of Parkinson's disease.  Choline alphoscerate is probably, among choline-containing phospholipids, the most effective in enhancing in vivo ACh release and was also investigated with positive results on cognitive domain in patients affected by AD, cerebrovascular disorders and vascular dementia ..."

Reference