#2c-p

i'm going to do it anyway, you know?. I mean, i never say no to this kind of things, I just hope my poorly mind stability can handle it.

Thanks for your report (8

2C-P is a chem that I’m interested in but have never gotten the opportunity to try (yet!). It’s longer-lasting than the other 2C’s and is pretty visual. You can read about specific effects here, oral and nasal will be similar but of course snorting it will lead to a more potent experience. 

2C-P

Nope, the only chem in the 2C-X family I’ve tried is 2C-E. I have heard that its fairly potent, and lasts longer than the other 2Cs. You should check Erowid if you want to know more about it!

To a stirred solution of 138 g p-dimethoxybenzene in 400 mL CH2Cl2 there was added a suspension of 172 g anhydrous AlCl3 in 500 mL CH2Cl2 which contained 92.5 g propionyl chloride. After stirring for 1.5 h the reaction mixture was poured into 2 L H2O containing ice. The phases were separated, and the aqueous fraction was extracted with 2x100 mL CH2Cl2. The organic phase and the extracts were pooled, washed once with H2O, and then with 2x100 mL 5% NaOH. The solvent from the organic phase was removed under vacuum, yielding a deeply colored residue. This was distilled at 150-165 °C at 20 mm/Hg yielding 170 g of 2,5-dimethoxypropiophenone as a pale amber-colored oil. Acidification of the sodium hydroxide extract, extraction with CH2Cl2, and evaporation of the solvent, yielded 3 g of an oil that slowly crystallized. These solids, on recrystallization from MeOH, provided 1.0 g of 2-hydroxy-5-methoxypropiophenone with a mp of 47-48 °C. The same Friedel Crafts reaction, conducted on the same scale in CS2 rather than in CH2Cl2, required reduced temperature (5 °C) and a 24 h reaction period. This solvent variation, with the same workup and isolation, gave 76 g of 2,5-dimethoxypropiophenone as a pale amber oil boiling at 130-137 °C at 4 mm/Hg. A total of 150 g mossy zinc was amalgamated by treatment with a solution of 15 g mercuric chloride in 1 L H2O. After swirling for 0.5 h, the H2O phase was removed by decantation and the zinc added to a 1 L three neck flask. To this there was added 20 mL H2O and 20 mL concentrated HCl, followed by 20 g of 2,5-di-methoxypropiophenone dissolved in 50 mL EtOH. This mixture was held at reflux with a heating mantle overnight, with the occasional addition of HCl as needed to maintain acidic conditions. After cooling to room temperature, the residual solids were removed by filtration, and the filtrate extracted once with 100 mL CH2Cl2 (this was the upper phase). Sufficient H2O was then added to allow extraction with 2x100 mL additional CH2Cl2 with the organic solvent being the lower phase. The combined organic extracts were washed twice with 5% NaOH, followed by one washing with dilute acid. Removal of the solvent under vacuum yielded 18 g of a dark brown oil that was distilled at the water pump to yield 7.2 g of 2,5-dimethoxypropylbenzene as a light yellow oil boiling at 90-130 °C. A mixture of 22 g 2,5-dimethoxypropylbenzene, 23 g POCl3 and 22 g N-methylformanilide was heated on the steam bath for 1.5 h. The hot, dark reaction mass was poured into 1 L H2O, which allowed the eventual separation of 2,5-dimethoxy-4-(n)-propylbenzaldehyde as a clear yellow oil weighting 14 g. Although the homologous 4-ethyl and 4-butyl benzaldehydes were clean crystalline solids, this propyl homologue remained an oil. Gas chromatographic analysis showed it to be about 90% pure, and it was used as obtained in the nitrostyrene steps with either nitromethane (here) or nitroethane (under DOPR). To a solution of 13 g 2,5-dimethoxy-4-(n)-propylbenzaldehyde in 100 mL nitromethane, there was added 1.3 g anhydrous ammonium acetate and the mixture held at reflux for 1 h. Removal of the solvent/reactant under vacuum yielded a spontaneously crystallizing mass of orange solids that was removed with the help of a little MeOH. After filtering and air drying there was obtained 7.5 g 2,5-dimethoxy-beta-nitro-4-(n)-propylstyrene with a mp of 118-122 °C. Recrystallization from CH3CN gave an analytical sample with a mp 123-124 °C. Anal. (C13H17NO4) N. In a 1 L round bottomed flask with a magnetic stirrer under a He atmosphere there was added 120 mL 1 M LAH in tetrahydrofuran. This stirred solution was cooled with an external ice bath, and there was added, dropwise, 3.2 mL of 100% H2SO4, freshly made by the addition of 13.5 g 20% fuming H2SO4 to 15.0 g of ordinary 96% concentrated H2SO4. When the addition was complete, a total of 7.2 g of dry 2,5-dimethoxy-beta-nitro-4-(n)-propylstyrene was introduced as solids in several batches, against a flow of He, over the course of 20 min. The reaction mixture was allowed to come to room temperature, and stirred for an additional 0.5 h, then brought to reflux for 10 min on the steam bath. The excess hydride was destroyed with 18 mL IPA, and then sufficient 15% NaOH was added which made the aluminum oxides distinctly basic and of a filterable texture. The inorganics were removed by filtration, and the filter cake washed with additional THF. The combined filrate and washes were stripped of solvent, yielding several g of a pale yellow oil that was suspended in a large quantity of dilute H2SO4. The aqueous phase was filtered free of insolubles, washed with a little CH2Cl2, and made basic with aqueous NaOH. This was extracted with 3x40 mL CH2Cl2 and, after the removal of the solvent under vacuum, the residual 2 g of off-white oil was distilled. A fraction that distilled at 100-110 °C at 0.3 mm/Hg was water white, weighed 1.59 g and spontaneously crystallized. This fraction was dissolved in 7.5 mL warm IPA and neutralized with 0.6 mL concentrated HCl. The spontaneous crystals of 2,5-di-methoxy-4-(n)-propylphenethylamine hydrochloride (2C-P) were suspended in 20 mL anhydrous Et2O, filtered, Et2O washed, and air dried. The weight was 1.65 g and the mp was 207-209 °C with prior sintering at 183 °C., Anal. (C13H22ClNO2) N.