SolemnRosary

apparently, cats' kidneys tend to be the thing that takes them down, something about their bodies being unable to self-clean their kidneys, and the vaccine is supposed revitalize the body's ability to do just that. It would be very VERY fucking cool to have cats suddenly reaching 30 years of age be the normal thing.

dude cracked the case about WHY kidneys fail, across the board as far as i can tell. turns out there's a specific molecule whose job it is to attach to waste and signal macrophages to come eat it. it remains inactive in cats for some reason, but the molecule is still there. basically what he's done is found the switch to activate them. this will be profound not only for our domestic babies, but for big cats too - especially cheetahs!

although his research was focused on cats, it's already being used to develop drugs for humans too!

on top of that, since these molecules are tags for waste, this could also dramatically lower the rate of fatty liver disease, liver cancer, urinary crystals, rheumatoid arthritis, and even some neurological cases! like, they're hoping it may have an impact on parkinson's and alzheimers, but it DOES have an impact on stroke recovery. like. holy shit.

furthermore, he's insisting that the feline drug be affordable if and when it rolls out onto the market. he wants this to be something anyone can get for their cat!! idk how much sway he'll have over the human drug, but hopefully enough that it, too, won't be that expensive.

annnnnd in his research that he's still doing for the human side of things, he's found a potential link between this molecule and estrogen. in the 20,000 samples he's tested, women between ages 10 and 29 had the highest amount of this molecule present in their blood (a higher amount means Something Fucky is going on, essentially. There's a higher amount of waste the body is trying to clean out) but it drops down to be almost equal amongst men and women after menopause. it hasn't been looked into yet, but fuck, just the fact it's noted and known and probably WILL be looked into soon??? imagine if this is what leads to figuring out all the various ways the ovaries and uterus fucks with people and how to fix it. or even like, maybe there's something about estrogen that makes it work better. who knows! but it's rad the link is there to be researched :D

As for the study itself, the 360 day follow up on stage 3 kidney failure kitties showed that the control had a survival rate of about 20%, while the test group had a survival rate of 80%

Shockingly, however, spending most of your time in close proximity to 500 pounds of liquid mercury is Not Great For One’s Health and tons of lighthouse keepers started to go crazy from the whole. Mercury poisoning thing. Hence why there are a lot of “haunted” lighthouses or wickies that lose it and maybe do a bit of manslaughter.

In a letter written on April 19, 1825, Augustin Fresnel proposed the use of mercury to reduce the friction in revolving lenses. His statement follows: “I propose to float our rotating devices, of the first order, in a bath of mercury, instead of placing them on rollers. This project won't present many difficulties; nevertheless, as I have not put it into execution, I won't require you to adopt it for your first lighthouse.”

Fresnel’s plan for mercury flotation was not put into practice until 1890 when Monsieur Leon Bourdelles, Chief Engineer of the French Lighthouse Service, designed and built a workable mercury flotation system. The mercury bath allowed the lens to operate in an almost frictionless environment and, additionally, allowed the speed of rotation to be dramatically increased.

It mattered for optics reasons.

Under less-than-ideal conditions, you can only see the beam when it’s pointed more or less directly at you. In-between beams you would not be able to see anything. One solution to this was to create multiple beams, and the lenses Mr Fresnel designed usually created 8 beams. But, even still, duration between flashes could be as long as one minute in the old mechanical roller systems.

The nearly frictionless operation of the Mercury suspension system allowed the lenses (large pieces of precisely ground glass weighing several hundred pounds in some cases) to rotate fast enough that they could be redesigned to create fewer (usually 3) beams. Fewer beams from a similar light source will be proportionally brighter, and the gains in speed were sufficient that duration between flashes could still be reduced to as little as 10 seconds.

This was a big upgrade. It didn’t just make the lighthouse signal faster, it allowed them to completely overhaul the lens and derive more visibility from a light source.

Secret sanctuaries 💧