ASCO 2019 Lung Cancer: 36 Oral Presentations of the ASCO19 lung cancer track summarised
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ASCO 2019 Lung Cancer: 36 Oral Presentations of the ASCO19 lung cancer track summarised

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Venetoclax FDA approved for CLL and SLL
Ramucirumab FDA approved for hepatocellular carcinoma
FDA approves avelumab plus axitinib for renal cell carcinoma
T-DM1 FDA approved for early breast cancer

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Ivosidenib FDA-approved as first-line treatment for AML patients with IDH1 mutation
Palbociclib approved for the treatment of male breast cancer
Atezolizumab +/- cobimetinib vs regorafenib for previously treated metastatic colorectal cancer (IMblaze370)
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Happy Chinese New Year 2019

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Trastuzumab-biosimilar Ontruzant® FDA approved in several indications
ERAS guidelines for antenatal and preoperative care in caesarean delivery
Cabozantinib FDA approved in HCC patients failing sorafenib
Erasmus University MC investigating a new surgical matrix to reduce post-operative complications
Keytruda® FDA approved for recurrent and metastatic Merkel cell carcinoma

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Calaspargase pegol-mknl (Asparlas®) FDA approved in paediatric and young adult acute lymphoblastic leukaemia (ALL) patients
It is thought that immune-checkpoint inhibitors could exacerbate chronic hepatitis B and C by enhancing T-cell cytotoxicity to viral antigens. The effects of PD-1, PD-L1 and CTLA4 inhibitors on HBV and HCV have largely been unreported. Most studies with I-O drugs excluded patients with chronic viral hepatitis. However, recent trials investigating I-O in HCC included subjects who were known hepatitis B and C carriers.
I-O in Special Populations: Chronic Viral Hepatitis Carriers https://medipr.org/2QwU1ps #BMS #Bristol-MyersSquibb #CTLA4 #HBV #HCV #hepatitis #I-O #nivolumab #Opdivo #PD-1