1.04 - The Tower Job

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1.04 - The Tower Job

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are you guys hearing about this dude working to developing a vaccine for cats that he's hoping would like. theoretically double their lifespans?
turns out i wasn't making that up, his name is Dr. Toru Miyazaki! he also wrote a book called "The Day Cats Live To Be Thirty", so cats are kind of his thing.
apparently, cats' kidneys tend to be the thing that takes them down, something about their bodies being unable to self-clean their kidneys, and the vaccine is supposed revitalize the body's ability to do just that. It would be very VERY fucking cool to have cats suddenly reaching 30 years of age be the normal thing.
As they age, almost all cats develop kidney disease, from which they eventually die. Just as in humans, kidney disease i
Dr. Toru Miyazaki’s AIM injection for cat kidney disease enters trials in 2025, aiming for a 2027 release. Greycoat Research supports the sc
whoa wait i actually read the articles and it's so much cooler than just that!!
dude cracked the case about WHY kidneys fail, across the board as far as i can tell. turns out there's a specific molecule whose job it is to attach to waste and signal macrophages to come eat it. it remains inactive in cats for some reason, but the molecule is still there. basically what he's done is found the switch to activate them. this will be profound not only for our domestic babies, but for big cats too - especially cheetahs!
although his research was focused on cats, it's already being used to develop drugs for humans too!
on top of that, since these molecules are tags for waste, this could also dramatically lower the rate of fatty liver disease, liver cancer, urinary crystals, rheumatoid arthritis, and even some neurological cases! like, they're hoping it may have an impact on parkinson's and alzheimers, but it DOES have an impact on stroke recovery. like. holy shit.
furthermore, he's insisting that the feline drug be affordable if and when it rolls out onto the market. he wants this to be something anyone can get for their cat!! idk how much sway he'll have over the human drug, but hopefully enough that it, too, won't be that expensive.
annnnnd in his research that he's still doing for the human side of things, he's found a potential link between this molecule and estrogen. in the 20,000 samples he's tested, women between ages 10 and 29 had the highest amount of this molecule present in their blood (a higher amount means Something Fucky is going on, essentially. There's a higher amount of waste the body is trying to clean out) but it drops down to be almost equal amongst men and women after menopause. it hasn't been looked into yet, but fuck, just the fact it's noted and known and probably WILL be looked into soon??? imagine if this is what leads to figuring out all the various ways the ovaries and uterus fucks with people and how to fix it. or even like, maybe there's something about estrogen that makes it work better. who knows! but it's rad the link is there to be researched :D
man just think, not only could our kitties start living longer, healthier lives, but just maybe dialysis will become as rare and obsolete as the iron lung is for people. what a badass Dr. Toru is!
"But I don't want to turn people into dinosaurs. I wanna cure kittie kidneys!"
Update: So they have done clinical trials and have submitted it for approval as of april 2026. They are expecting it to be available late 2026/early 2027
The AIM protein drug for feline chronic kidney disease has been submitted for approval in Japan (April 2026). We break down clinical trial d
As for the study itself, the 360 day follow up on stage 3 kidney failure kitties showed that the control had a survival rate of about 20%, while the test group had a survival rate of 80%
New 2026 study: AIM protein boosts cat kidney disease survival from 20% to 80%. Discover how this scientific breakthrough is changing the fu
Our cat Scout is in the early stages of kidney disease. This might be available in time to save her!
I love how Zohran Mamdani is wearing a suit everywhere. And if he has anything else he puts it ON TOP of the suit. A basketball jersey. A high-vis vest. All worn over the suit. He’s like the mayor character in a cartoon who’s always dressed as The Mayor. If I didn’t know who he was and he biked past me in NYC I’d be like holy shit was that the mayor
I know his tailor is stressed bro look at this man wearing a suit to fix a pothole
I bet he opens his closet to the same suits with some slightly different ties like SpongeBob.
I bet if he took off his suit there’d be a suit underneath
important update
Academy Award for Best Animated Feature:
That person who helps others simply because it should or must be done, and because it is the right thing to do, is indeed without a doubt, a real superhero.
Spider-Man: Into the Spider-Verse (2018, dir. Bob Persichetti, Peter Ramsey and Rodney Rothman)

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MONSTERS INC. (2001) Dir. Peter Docter
Dr. Grace? Project Hail Mary (2026) dir. Phil Lord, Chris Miller
10 Things I Hate About You dir. Gil Junger | 1999
For a city to be walkable. It must also be sittable.
#every time I read this phrase the same thing happens#I read it as shittable and go wait that can't be right#oh right they were talking about public benches that makes more sense#but public bathrooms available without fees should also be a thing tho#cities should definitely be shittable#it happens EVERY SINGLE TIME
it must also be shittable
the raven (1845) - edgar allan poe
op change ur fucking url
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@tvarchive tv appreciation week ↳ day 1: first tv obsession
Brooklyn Nine-Nine (2013-2021) by Micheal Schur and Dan Goor
Sense and Sensiblity (1995)
Alan Rickman as Colonel Brandon
nobody:
literally not a single fucking person:
me: actually if i was going to handle silmarils i no longer have any right to because i killed people and shit, i would simply not touch them bare handed. i, being an intellectual who knows that these stones burned the innards of a literal werewolf, a creature whose own stomach acids probably had the same corrosive effect as lava, am perfectly aware that my silly little tummy (which throws tantrums about dairy) is no match. a silmaril would give me instant stigmata. carve a perfect tunnel through my flesh. i, being clever and possessing the ability to look up at the sky, am equally aware that eärendil’s newest labret piercing being visible to the naked eye from the stratosphere makes it pretty clear that the thing is probably very bright. as bright as a star. neil armstrong walked on the moon in a space suit. he did not wank off the stars in his birthday suit. all things considered, i, unlike maedhros fëanorian who spent the first 500 years of his life eating hot chip, specialising in himbodom, lying, and not educating himself on basic physics, i would be trotting away peacefully from eönwë’s camp, my silmarils clenched victoriously in
I think it's not a coincidence this sounds like a plan that Pippin would propose at the Council of Elrond only to get shot down by Boromir and Gandalf simultaneously for different reasons.
anyway sound off. at what stage do ppl think Han figured out the Force was real. the boring answer is after seeing Obi-wan vanish but i think he could rationalise that away as his eyes playing tricks on him. what do we think.
Let me demonstrate my answer for you:
That's it. That's my answer. Endor.
Please just take a look at Han's face right after witnessing 3po float. The man just had his entire worldview blown to smithereens.
that's so funny. that means he accepted Vader deflecting a blaster bolt with his hand as just something freaky government cyborgs can do, and stuck by Luke for multiple years as he tried to figure this Force stuff out, and just treated it like your friend getting really really into neopaganism to cope with a loss.
like yeah kid good job with the witching. i'm certain it will be more useful against your enemies than your sharpshooting. no i do not think your witchcraft is supplementing your aim but i'm not gonna argue about it.
yeah Luke was like 'I heard Ben Kenobi's voice in my head telling me how to blow up the Death Star :)' and Han was like 'kind of an unusual coping mechanism but I'm not gonna argue with him'
thanks to carbonite han not only misses learning about luke's training montage on dagobah, he's also half-blind during their whole escape on tatooine. luke's out there force-kicking henchmen with his gucci boots and doing flips and shit and han can't see a goddamn thing. now on endor luke's yeeting threepio with the power of his mind and han's just like 'the last time we hung out i had to stuff him in a tauntaun sleeping bag'.
@softness-and-shattering I hate you I hate you I hate you
"rickrolling is mean" rickrolling is the gentle, kind, prosocial descendant of what we used to do on the internet, which was putting a redirect to goatse in every possible misspelling of a url
Rickrolling is deceptive, but it's among the most harmless forms of deception available
in other words, it may tell a lie, but it will never tell a lie and hurt you

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i recently found out the funniest thing about big horses recently which is that for centuries humans have sworn that the feathering on big horse’s legs has been bred in there for a reason, and the reason given is usually something to do with how it helps keep the joints warm and safe when the big horse is doing hauling work in fields.
the thing is: it doesn’t appreciably do that, because the feathers wick up water and mud, which cancels out any insulation advantage they might hypothetically confer, and also it wasn’t even put there on purpose.
the Leg Get More Hair gene is just linked to the Bones Get More Big gene. when you breed any lineage of horses to have bigger bones–not just taller, but chunkier–the leg hair just happens anyway. so every single breed of draft horse has feathered legs, and even carriage horses like friesians get feathers once they hit a certain threshold of lorge.
when you supersize your horse, mother nature throws in a free pair of booties. how cool is that?
To Americans who might feel inclined to scoff at Europeans talking about the heat: I know you’ve heard this before but maybe you’ll listen to an American who spent many years of her life dealing with 115F / 46C summers out in the American west and now lives in France.
THIS IS WORSE. It’s so much worse.
When you hear “there’s no AC” you probably are thinking like…oh that’s rough, but still I’ve dealt with those temps. My old place didn’t have AC. It can’t be that bad.
NO. The lack of AC trickles down into every facet of dealing with the heat in a way that slowly and quite literally boils you alive. It’s not just “oh my apartment is hot this sucks”, it’s “there is nowhere you can go to cool down and if you overheat there is no help available”
For most there’s no AC anywhere. Anywhere. The coolest place available is maybe your local church, or a shopping center. Both will kick you out around 8pm, the hottest part of the day. In France and Spain in particular, the time zone is wrong (Hitler’s fault—we’re still aligned with Germany instead of the UK) and the sun doesn’t set until 10-11pm. Heat is still being actively pumped into your living spaces at 10pm.
And the temps do not meaningfully drop overnight. (Which you might expect if you’re from the American west. Southerners do understand this.) Many people live in stone walled buildings that just keep heating up. This is very literally the experience of being in a stone oven. And there’s no way to drop the temperature. You can’t escape it.
If your body temp climbs to unmanageable levels and you start experiencing heat exhaustion, you can call the hospital…most of which also do not have AC. I’m not sure how they’re treating people, I guess with ice packs? There’s already been a handful of deaths in my city, and that’s before any kind of post-wave reporting. These are real time reported deaths.
Anyway I want you to really, really internalize the sense of panic that starts to set in when you’re in these circumstances. The animal brain really starts to go wild when there’s no options and no escape. That’s why Europeans are posting about suffering.
(And no—leaving isn’t possible either. Many people don’t have cars, and the trains are down due to track over heating. And also don’t have AC. These conditions are frankly genuinely scary.)