#shigella

chappell roan & gerard way outfit/performance parallels, PART 3!!!

blue suit w/ red tie: promotional photo for the giver, february 2025 / promotional photo for hesitant alien, 2014

jester/clown: edinburgh summer sessions, august 26-27 2025 / swarm berlin, june 12 2022

bat: reading festival, august 22 2025 / swarm new jersey night 1, september 20 2022

swan: the tonight show starring jimmy fallon, june 20 2024 / swarm boston night 1, september 7 2022

puppet: shigella for visions of damsels & other dangerous things, summer 2025 / the gentleman for long live the black parade, summer 2025

I wanna go back so bad

Jammed Transmission

A driver in a traffic jam blasts an annoying catchy song. The next driver hears it, and whistles along. Then another hums it, and soon the whole street is a cacophony of unsynchronised earworms. The song might have been contained within the first car by a closed window, and that’s what a new molecule may do for dysentery-causing Shigella flexneri infections, which spread between cells lining the intestine's colon. The bacteria use a host cell’s internal skeleton to create protrusions towards neighbouring cells, which bud off as sac-like structures known as vacuoles to transmit the infection. A study identified a protein required for this conversion from protrusion to vacuole, and a molecule that inhibits it, thus preventing spread (pictured, red bacteria limited to isolated spots in an infected rabbit colon after treatment with the inhibitor). This could be a new route to treatment for a condition with no vaccine and increasing risk of drug resistance.

Written by Anthony Lewis

Image from work by Steven J. Rolland and colleagues

Department of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, VA, USA

Image originally published with a Creative Commons Attribution 4.0 International (CC BY-NC 4.0)

Published in PLOS Pathogens, May 2025