2021 Mercedes S580 buyer's guide: 496 hp specs, every trim line and package price, what one costs used, and what to inspect.
2021 Mercedes S580: $116,300 new, about $54,500 now
The W223 S-Class was the most technically ambitious car Mercedes had ever built. Five screens, an OLED dash, a fingerprint reader, rear passenger airbags, 64-color ambient lighting, and a 496 hp twin turbo V8 that Car and Driver ran to 60 in 3.9 seconds.
It also lost more than half its value in 5 years, which is the part that makes it interesting instead of just expensive.
The depreciation table tells the story better than any review does. $24,872 gone in 2023. $11,782 in 2024. $10,732 in 2025. And $749 in the last 12 months. The fall is over. What is left is maintenance, and on a car with this much content, maintenance is the whole conversation.
Full breakdown: every trim line and what it cost, all 11 exterior colors, the AMG Line versus Executive Line difference that most listings get wrong, current used pricing, and what to inspect before buying.












