#neuropathology

꒷꒦︶꒷꒦︶ ๋ ࣭ 🩻꒷꒦⁺‧₊˚ ཐི⋆♱⋆ཋྀ ˚₊‧⁺ ๋ ࣭ 🔬꒷꒦꒷꒦︶꒷꒦︶

Content warning:

mentions of illnesses, amputations and medical malpractices !! IM STILL A STUDENT, some things may not be fully exact, dont take this post as a self diagnosis tool!!

Characters mentioned: 096, 106, 049, 073.

: ̗̀➛ Scp-096 the shy guy

Scp-096 is a very interesting character to me, showing clear human like behavior, even tho he cannot be biologically described as one. I wanted to make this short but there are just way too many peculiar aspects about this scp i just needed to explain them in depth.

Angelman syndrome — Angelman syndrome is an intellectual disability caused by neurogenetics. It causes speech impediment, the patients often having little to no ability to communicate, slow intellectual development, those affected often having the brain development of a few months old to three/four years old toddler and ataxia, which causes poor balance and difficulty to move and affects also coordination.

The reasons i headcanon 096 to have this disorder is mainly due to his description on the wiki files, him having developed a brain circa the age of a two years old, plus all we know about his way of communication is thru screaming and crying, which added up to why i would hc him with Angelmans.

Mixed anxiety-depressive disorder (MADD) with dysthymia — MADD is a psychological condition characterized by a continuous and apparently unexplainable state of depression, stress and anxiety. The symptoms may be both physical and psychological, causing persistent feelings of fatigue, headaches and tachycardia, with common signs of paranoia and isolation. People suffering from this disease often experience some (not fully) symptoms of other disorders like ocd, bpd and other kinds of schizophreniform diseases.

I think its quite useless to explain why i hc him to have this disorder :’)

Physical anorexia — differently from nervous anorexia, physical anorexia is a – sorry for the repetition – physical disorder in which the individual has troubles eating not because of dysmorphia but because of stomach centered issues such as gastritis, heavy food intolerances or indigestion, gastrointestinal acidity or just not feeling the brain imput of eating

Depersonalization-derealization disorder (DPDR) — is a mental disorder that makes you unable to recognize yourself or the way you perceive the world around you. This disorder is characterized by a costant feeling of detachment from your own body, thoughts or actions, sometimes making the person suffering it impulsive and unresponsive of their own doings.

꒷꒦︶꒷꒦︶ ๋ ࣭ 🩻꒷꒦⁺‧₊˚ ཐི⋆♱⋆ཋྀ ˚₊‧⁺ ๋ ࣭ 🔬꒷꒦꒷꒦︶꒷꒦︶

: ̗̀➛ SCP-106 the old man

Before i proceed, i want to specify that my hcs for him follow the “ww1 soilder lore”

Also im begging you please to stop calling him radical Larry since its an ableist terminology used for soilders that got permanently injured during the war.

With that out of the way lets dive in

Shellshock ptsd — shellshock or combat stress ptsd, is a mental condition that lot of soldiers from ww1 developed from the trauma of the trenches. For many its a clearly visible disorder, with symptoms such as frequent and constant shaking, sunken and wide open eyes, speech difficulties and often severe panic attacks, for some others tho its more of a triggered trauma response, such as being scared of loud, unexpected sounds, repeating war-like habits in certain situations ecc.

For me, 106 falls more under the last category, not showing many physical signs of shellshock, even if still presents, but more of how the war affected him mentally.

Monoplegy — monoplegy is a paralysis, either temporary or permanent, of one singular limb. It may be caused by either a neurological or physical injury or can be genetic. For temporary paralysis, the most common symptoms are severe pain in the limb, followed by a “pulling” sensation in the muscle followed by stiffness and then the full numbness of the limb.

For him, i hc that he was heavily injured during war from multiple gunshot wounds in his leg, hence why the nickname that was given to him, and that he is now periodically paralyzed in that same leg because of poor medical help he was given at the time, probably, knowing medical war history, they tried to pull out the bullets, resulting in more nerves and muscular tissues damage, ending up in making that limb completely useless, even after healing.

Andersen-Tawil syndrome — directly tied to his monoplegy, ATS is a disorder that causes cardiac arrhythmia, making your heart beat either faster or slower, followed by a low blood flow in the interessed limb, causing the collapse of the said limb and sudden numbness. It can also be associated with hypokalemicy, aka low potassium in the body vessels.

The reason i hc him to have low potassium in his body is, well, because i hc his potassium to be ON him. I like to think that his body cannot physically contain the potassium his cells produce and spills it out from his pores together with the corrosive ooze (hence why the brown color of the mixture)

꒷꒦︶꒷꒦︶ ๋ ࣭ 🩻꒷꒦⁺‧₊˚ ཐི⋆♱⋆ཋྀ ˚₊‧⁺ ๋ ࣭ 🔬꒷꒦꒷꒦︶꒷꒦︶

: ̗̀➛ SCP-049 the plague doctor

Almost all my headcanons for him are mental illnesses more than physical ones since hes, you know, a doctor, so he takes a maybe good care of his own body

Autism — yeah i know i didnt even have to say it we all know he is autistic. By the way, autism is a genetic pathology that afflicts the brain development, changing the way a person experiences social interactions, stimulus or communication, making the individual who has it to have specific routines, patterns or behaviors. It also affects your sensory perception of things and can vary one’s senses on a psychological level more than physical. Sometimes, autistic individuals tend to speak in one singular monotone, sometimes they may show traits of other commonly associated disorders such as ocd and social anxiety (which i hc he has both of those, traits like speaking, heavy on social anxiety)

Attention Deficit Disorder (ADD) — a disorder that, just like ADHD, affects your ability to focus, except minus the hyperactivity part, meaning that your brain activity does focus only on one thing at time, blocking out everything else, hence why the attention DEFICIT.

I hc 049 being sometimes so hyperfocused on his researches to often forget everything else around him.

Third person Munchausen Syndrome paired with paranoid disorder — so, before i get into this, what is munchausen syndrome; its a disorder called “the fake illness disorder” where the individual fakes symptoms of a disease to make people think they have it. Now, im NOT saying he has munchausen, but he has more of a paranoid personality disorder (also known as a delusional disorder), making him see symptoms in OTHER people that aren’t actually there (heres why third person munchausen). Paranoid personality disorder, not to get mixed with paranoia, is a mental disorder that makes an individual believe in something so firmly that they cant recognize what is real outside their own reality. Paranoid people tend to act just normally during the day, since its more of an internalized disorder, but may have psychotic like episodes whenever their delusion is brought up.

Yes this is about the pestilence.

C type thoracolumbar kyphosis— kyphosis is a spinal deformation caused by multiple causes, in 049 case by sitting slouching too long throughout the years and mostly due to his own height. It is notable from the “hunchback” relaxed posture one affected will get. In his case i think it may be thoracolumbar (from T1 to L2). C shape stands for the way the “curve” of the kyphosis is shaped, meaning its one long curve and not multiple curves. Even tho not really noticeable (between level 1 and 2, and a bending forward angle of 15° at radiography) it will cause him back pains and physical fatigue.

Also i think he may be slightly myopic and have a lazy eye.

꒷꒦︶꒷꒦︶ ๋ ࣭ 🩻꒷꒦⁺‧₊˚ ཐི⋆♱⋆ཋྀ ˚₊‧⁺ ๋ ࣭ 🔬꒷꒦꒷꒦︶꒷꒦︶

: ̗̀➛ SCP-073 Cain

I may yap a bit about prosthetics and amputations here so beware

Pedicle screws — implants that are used as a spinal prosthesis to keep fused vertebraes apart from each other, the implants work as a support of part or the entire spine with the aid of a “neil” that gets inserted inside the vertebrae, a metal bar that keeps the spine anchored and upright, and, using the funnel method, a screw will be placed between each vertebrae.

Trans humeral myoelectric prosthetics — a kind of prosthetic that uses the EMGs (electrical signals) that the muscle produces to move itself. While i hc them to be osseointegrated (internal prosthetics), i believe that the foundation was originally planning to have him keep an external prosthetic, for the surgery to change them every time they would get ruined would have caused the ones doing it to feel a great amount of pain. I also believe that when he got taken in the foundation, his prosthetics weren’t as advanced as they are now, getting provided with only some cosmetic prosthetics that barely did any movement at all, the stumps in his legs were barely molded into a socket and the liner didnt match the entrance of the prosthetic.

Thicker Myelin — Myelin is a protective coating around nerve fibers that helps brain signals travel faster and it is thought that people with higher IQs may have thicker myelin, allowing information to move more quickly through the brain.

Stronger synaptic connection and density of dendritics — some brains with stronger cerebral activity often have more numerous connections between brain cells, this is oten linked to higher IQ and to larger and more complex neurons, especially in areas of the brain involved in thinking and understanding. These neurons have more branches, which helps brain signals start faster and allows the brain to process and store information more efficiently. I personally think that Cain, being an intelligent individual that lived for longer than anyone else on earth, has developed a strong brain activation that makes him able to remember and connect all pieces of information he accumulated during the years.

Thats all for todays post

hoped you enjoyed it and didn’t bore yalls soul out of existence 🫩🙏🏽 let me know if you want a part 2 :3

On June 14, 1864, Alois Alzheimer was born in the small Bavarian town of Marktbreit, Germany. He would go on to become one of the most important figures in modern neuroscience, giving his name to one of the most studied neurodegenerative conditions in history, Alzheimer Disease.

Alzheimer trained in medicine at the universities of Aschaffenburg, Tübingen, Berlin, and Würzburg. Early in his career, he focused on psychiatry and brain pathology at a time when mental illness was still poorly understood and often misdiagnosed. His meticulous approach to brain research combined clinical observation with microscopic analysis, helping bridge psychiatry and neurology.

His most famous contribution came in 1906, when he described the case of a woman known as Auguste Deter, who had suffered severe memory loss, confusion, and behavioral changes. After her death, Alzheimer examined her brain and identified abnormal protein deposits and tangled nerve fibers—later recognized as hallmark features of the disease that now bears his name.

Necrosis of the pyramidal neurons

The classic necrotic neuron is the "dead red". Shrunken, angular, and hypereosinophilic (red) with a pyknotic nucleus, scattered dead neurons can be associated with a wide range of neurologic disease. Necrosis of the pyramidal neurons in the hippocampus is commonly associated with seizure activity, particularly in the CA2 and CA3 regions. Whether this necrosis is the cause or effect of the seizure activity is not always entirely clear, although it is typically attributed to the abnormal electrical activity and hypoxia associated with seizures.

Would you care for some actual academic content? My Pathology IV Exam II is tomorrow at 2pm. I've gone through everything once, but (expected) my brain is still a little scattered. Unable to access a giant dry erase board, we get...this.

It's the first two lectures of the exam content. The next several are over syndrome with cranial nerves and overlap enough, I'll attempt to put the big ones all on one page and the individual ones on other page(s).

But! I also have nearly 3 hours of mandatory zoom meeting before that exam. So, we'll see.

Tuesday, 11:40 am