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Digitalis ECG
β Also called cardiac glycosides
β Digitalis are in fact only small positive inotropic with some peripheral vascular effects.
β At the level of myocardial cell, digitalis bind to membrane receptors and inhibit Na + / K + ATPase membrane.
This blocks the outlet of extracellular Na + => [Ca2 +] int high (Na + exchanger / Ca2 +) => increasing the contractile force of the myocardial cell.
β Digitalisβ¦
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