#developmental anomaly

crooked

Sharpie stain

I collect pictures of weird kittens and compile them here! Consider this a tag-organized archive of ugly babies. Feel free to submit freaklets (and your own weird looking cats) via the ask function! All images must be sourced if not taken by you.

Some of the breeds featured on this blog have health problems! Please do your own research if you're thinking about getting a purebred cat.

General tags: #daily freaklet #not a daily freaklet #video #reblog

Grub: #grub

Colors: #white #black #orange #gray #golden #sable

Patterns: #tabby #solid #bicolor #tricolor #tuxedo #colorpoint

Fur textures: #hairless #rexed

The most prevalent developmental anomaly in humans is dental agenesis, which frequently poses a serious clinical issue.

It is classified based on the number of missing permanent teeth, excluding third molars.

Oligodontia refers to the absence of multiple teeth (more than six teeth), excluding the third molars.

If oligodontia is part of a syndrome, there are usually changes to the skin, nails, eyes, ears, or skeleton.

The most recent gene found to be responsible for oligodontia is an autosomal recessive mutation in LTBP3, the gene that encodes latent TGF-b binding protein 3, an extracellular matrix protein thought to be necessary for osteoclast function.

When teeth are suspected to be missing, a clinical examination is conducted along with a panoramic radiograph (and intra-oral X-rays if needed).

Oligodontia is suggested by the delayed eruption of teeth, persistence of primary teeth, alveolar bone hypotrophy, and the presence of diastemas.

Persons with tooth agenesis currently have a variety of treatment options.

Generally, the replacement of lost or deficient tissues is based on drug therapies, the use of different prosthetic materials and implants, and tissue/organ transplantations.

Synthetic dental implants are a common standard procedure for replacing missing teeth, and their success has grown in recent decades.